Bushnik Tamara, Englander Jeffrey, Wright Jerry
Rehabilitation Research Center, Santa Clara Valley Medical Center, San Jose, Calif 95128, USA.
J Head Trauma Rehabil. 2008 Jan-Feb;23(1):25-32. doi: 10.1097/01.HTR.0000308718.88214.bb.
This study used a prospective longitudinal design to quantify fatigue and associated factors during the first 2 years after traumatic brain injury (TBI). Fifty-one individuals were assessed at 3 time points: within the first 6, 12, and 18-24 months after TBI. Self-reported fatigue improved during the first year, as did pain, sleep quality, cognitive independence, and involvement in productive activity. Further changes up to 2 years after TBI were not observed. The subset of individuals who reported significant increases in fatigue over the first 2 years demonstrated poorer outcomes in cognition, motor symptoms, and general functioning than those with decreased or stable fatigue.
本研究采用前瞻性纵向设计，以量化创伤性脑损伤（TBI）后前两年的疲劳及相关因素。51名个体在3个时间点接受评估：TBI后的前6个月、12个月以及18 - 24个月内。自我报告的疲劳在第一年有所改善，疼痛、睡眠质量、认知独立性以及参与生产活动的情况也是如此。未观察到TBI后2年期间的进一步变化。在头两年报告疲劳显著增加的个体子集，在认知、运动症状和总体功能方面的结果比疲劳减轻或稳定的个体更差。
