患有多器官功能障碍的危重新生儿：三级新生儿重症监护病房中通过NEOMOD评分进行评估
Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU.
作者信息
Janota J, Simak J, Stranak Z, Matthews T, Clarke T, Corcoran D
机构信息
Department of Paediatrics, The Rotunda Hospital, Parnell Square, Dublin 1, Ireland.
出版信息
Ir J Med Sci. 2008 Mar;177(1):11-7. doi: 10.1007/s11845-008-0115-5. Epub 2008 Jan 25.
BACKGROUND
The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality.
AIM
To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants.
METHODS
The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid-base balance in 24-h intervals during the first 28 days of life.
RESULTS
A NEOMOD of > or =9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality.
CONCLUSIONS
The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.
背景
新生儿多器官功能障碍评分（NEOMOD）可预测出生后28天内的死亡率，并提供影响死亡率的器官功能信息。
目的
测试NEOMOD在极低出生体重（VLBW）婴儿中的预测准确性和描述准确性。
方法
该系统应用于112例婴儿。它在出生后28天内每隔24小时评估一次中枢神经系统（CNS）、凝血功能、呼吸系统、胃肠道（GIT）、心血管系统（CVS）、肾脏系统和酸碱平衡。
结果
NEOMOD≥9与100%的死亡率相关。采用受试者工作特征（ROC）曲线评估NEOMOD评分预测死亡率的准确性。NEOMOD获得的死亡率曲线下面积（AUC）为0.93。
结论
NEOMOD可每日评估多器官功能障碍综合征（MODS）的严重程度，是死亡率的准确预测指标。
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