Luo Yi, Lu Yi, Lu Guosheng, Wang Man
Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Microsurgery. 2008;28(2):113-6. doi: 10.1002/micr.20460.
Our study was performed to investigate the operative effects of pediatric cataract surgery with anterior vitrectomy. The study comprised of 38 pediatric patients aged 2-5 years and involved a total of 60 eyes with congenital cataracts. The study was done between March 2004 and December 2005. Posterior capsulorhexis with anterior vitrectomy was performed on 34 eyes of 20 children, and cataract extraction was performed on 26 eyes of 18 children. The percentages of various complications and rate of neodymium YAG (Nd:YAG) laser capsulotomy were followed up for 12-36 months. There were significant differences in the percentages of posterior capsule opacification (PCO) and rate of neodymium YAG (Nd:YAG) capsulotomy between the anterior vitrectomy group and cataract extraction group (P < 0.01). The anterior vitrectomy group was associated with less posterior capsular opacification (11.8%) than the cataract extraction group (76.9%). The YAG capsulotomy rate was 2.9% for the anterior vitrectomy group, and 57.7% for the cataract extraction group. After operation the fibrous exudates in anterior chamber and the intraocular lens subluxation or capture were 5.9% and 2.9% for the anterior vitrectomy group while for the cataract extraction group they were 23.1% and 15.4%; the difference was statistically significant (P < 0.05). The results suggest that primary posterior capsulorhexis with anterior vitrectomy in pediatric cataract surgery who are between 2 and 5 years old is necessary and effective procedure with low PCO rate.
我们开展这项研究是为了探究小儿白内障手术联合前部玻璃体切割术的手术效果。该研究纳入了38例2至5岁的小儿患者,共涉及60只患有先天性白内障的眼睛。研究于2004年3月至2005年12月期间进行。对20名儿童的34只眼睛进行了后囊膜撕开联合前部玻璃体切割术,对18名儿童的26只眼睛进行了白内障摘除术。对各种并发症的发生率及钕钇铝石榴石(Nd:YAG)激光晶状体后囊切开术的发生率进行了12至36个月的随访。前部玻璃体切割术组与白内障摘除术组之间,后囊膜混浊(PCO)的发生率及Nd:YAG晶状体后囊切开术的发生率存在显著差异(P<0.01)。前部玻璃体切割术组的后囊膜混浊发生率(11.8%)低于白内障摘除术组(76.9%)。前部玻璃体切割术组的YAG晶状体后囊切开术发生率为2.9%,白内障摘除术组为57.7%。前部玻璃体切割术组术后前房内纤维渗出物及人工晶状体半脱位或夹持的发生率分别为5.9%和2.9%,而白内障摘除术组分别为23.1%和15.4%;差异具有统计学意义(P<0.05)。结果表明,对于2至5岁的小儿白内障手术患者,一期后囊膜撕开联合前部玻璃体切割术是必要且有效的手术,PCO发生率较低。