Schwartz M S, Swash M, Ryan J
Institute of Pathology, Royal London Hospital, U.K.
Neuromuscul Disord. 1991;1(5):365-9. doi: 10.1016/0960-8966(91)90123-a.
CT scanning of thigh muscles has shown that the gracilis is often relatively resistant to degeneration in neuromuscular disorders. We have compared the histometric features of the gracilis muscle with the biceps femoris and vastus lateralis muscles in the right and left thighs of 12 subjects without neuromuscular disease. There was striking variation between individuals, but marked similarities between the two limbs in individuals. The gracilis and vastus lateralis muscles contained fewer Type 1 fibres than the biceps femoris. The Type 2 fibres were slightly larger in vastus lateralis than in the other two muscles. There is thus no evident morphological difference between the gracilis muscle and other thigh muscles that can be correlated with the different susceptibility of these muscles in neuromuscular diseases. However, these muscles are subject to differing physiological stresses in movement, and these may be important in determining the response to disease.
大腿肌肉的CT扫描显示，在神经肌肉疾病中，股薄肌通常相对不易发生退变。我们比较了12名无神经肌肉疾病受试者左右大腿中股薄肌与股二头肌和股外侧肌的组织测量特征。个体之间存在显著差异，但个体的双下肢之间存在明显相似性。股薄肌和股外侧肌的I型纤维比股二头肌少。股外侧肌的II型纤维比其他两块肌肉略大。因此，股薄肌与其他大腿肌肉之间没有明显的形态学差异，而这种差异与这些肌肉在神经肌肉疾病中的不同易感性相关。然而，这些肌肉在运动中承受着不同的生理压力，而这些压力可能在决定对疾病的反应中起重要作用。
