Arisawa Emília Angela Loschiavo, Almeida Janete Dias, Carvalho Yasmin Rodarte, Cabral Luiz Antonio Guimarães
Health Science Faculty, Vale do Paraíba University - UNIVAP, Brazil.
Med Oral Patol Oral Cir Bucal. 2008 Feb 1;13(2):E94-7.
The aim of the present study was to analyze the main clinical and histopathological features of autoimmune diseases with oral manifestations such as oral lichen planus (OLP); mucous membrane pemphigoid (MMP); pemphigus vulgaris (PV) and erythema multiforme (EM).
Retrospective review of 5770 files from the Oral Pathology Laboratory of São José dos Campos Dental School, São Paulo State University (UNESP) comprising a 27-year period from 1974 to 2000.
The cases accounted for 64 (1.10%) of 5770 anatomopathological examinations performed over the study period. Among the autoimmune diseases diagnosed, 49 (76.56%) were OLP, 6 (9.37%) were MMP, 5 (7.82%) were EM and 4 (6.25%) were PV. Descriptive statistical analysis was used.
The initial manifestations of most autoimmune diseases occur in the oral mucosa, an earlier diagnosis and proper therapeutic protocol will delay the dissemination of the lesions, thus greatly contributing to a better prognosis and quality of life of the patient.
本研究旨在分析具有口腔表现的自身免疫性疾病的主要临床和组织病理学特征，如口腔扁平苔藓（OLP）、黏膜类天疱疮（MMP）、寻常型天疱疮（PV）和多形红斑（EM）。
对圣保罗州立大学圣若泽杜斯坎普斯牙科学院口腔病理实验室1974年至2000年这27年间的5770份档案进行回顾性研究。
在研究期间进行的5770次解剖病理学检查中，这些病例占64例（1.10%）。在诊断出的自身免疫性疾病中，49例（76.56%）为OLP，6例（9.37%）为MMP，5例（7.82%）为EM，4例（6.25%）为PV。采用描述性统计分析。
大多数自身免疫性疾病的初始表现发生在口腔黏膜，早期诊断和适当的治疗方案将延缓病变的扩散，从而极大地有助于改善患者的预后和生活质量。
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