Avetisov S E, Budzinskaia M V, Kiseleva T N, Kazarian E E, Gurova I V, Smirnova T V, Shcheglova I V, Privivkova E A, Loshchenov V B, Shevchik S A, Kuz'min S G, Vorozhtsov G N
Vestn Oftalmol. 2007 Nov-Dec;123(6):8-11.
The efficiency of photodynamic therapy (PDT) versus drug therapy was evaluated in patients with subretinal neovascular membranes (SNM) in complicated myopia (CM). Photosens (aluminum phthalocyanine) was intravenously injected in a dose of 0.05 mg/kg. The irradiation conditions were as follows: a session was carried out, using a laser at a wavelength of 675 nm, in an exposure light dose of 120 J/cm2. The number of sessions ranged from 3 to 5 a week, depending on the clinical picture of SNM. The total light dose was not greater than 500 J/cm2. Twelve months after drug therapy and a course of PDT, reduced visual acuity was observed in 50% and only 20.8% of cases, respectively. Stabilization or increase of visual functions occurred in the remaining patients receiving a course of PDT.