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[毒液中毒第六章:非洲的蝎蜇中毒]

[Envenomations VI. Scorpionism in Africa].

作者信息

Goyffon M, Billiald P

机构信息

Département régulations, développement et diversité moléculaire, Paris.

出版信息

Med Trop (Mars). 2007 Oct;67(5):439-46.

Abstract

Scorpionism is a serious public health problem in North Africa, sub-Saharan countries, and South Africa. The number of species involved is small, but some have large geographic areas of distribution. Fatal outcomes sometimes occur in children and young adults. In most cases the only symptom after a scorpion sting is intense, persistent pain. Appearance of digestive symptoms within a few hours after the sting (5% of cases) is a sign of severe envenomation. These symptoms can be followed by pulmonary edema and cardiovascular manifestations (arrhythmia and hypotension). Early death can occur due to cardiovascular failure (1 to 2% of untreated cases). Progression is rapid and, after a period of 24 hours, the patient is out of danger and will recover quickly with not sequels. Specific (serotherapy) and symptomatic treatment must be initiated as soon as possible after the sting. Envenomation of a child by a dangerous adult scorpion (more than 5 cm long) in summer should be considered as a medical emergency. Declining production of antivenom is a disturbing development.

摘要

蝎蜇伤在北非、撒哈拉以南国家及南非是一个严重的公共卫生问题。涉及的蝎种数量不多,但有些分布地域广阔。儿童和年轻人有时会出现致命后果。多数情况下,蝎蜇伤后唯一的症状是剧烈、持续的疼痛。蜇伤后数小时内出现消化症状(5%的病例)是严重中毒的迹象。这些症状之后可能会出现肺水肿和心血管表现(心律失常和低血压)。早期死亡可能因心血管衰竭所致(1%至2%的未治疗病例)。病情发展迅速,24小时后患者脱离危险,且不会留下后遗症,恢复很快。蜇伤后应尽快开始特异性(血清疗法)和对症治疗。夏季若儿童被危险的成年蝎(体长超过5厘米)蜇伤,应视为医疗急症。抗蛇毒血清产量下降是一个令人不安的情况。

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