锯齿蛋白2（Jagged2）在髁突软骨发育中的基因表达。
Gene expression of Jagged2 in mandibular condylar cartilage development.
作者信息
Shimizu T, Tsujigiwa H, Nagatsuka H, Nakano K, Okafuji N, Kurihara S, Nagai N, Kawakami Toshiyuki
机构信息
Matsumoto Dental University, Institute of Oral Science, Shiojiri, Japan.
出版信息
Eur J Med Res. 2008 Jan 23;13(1):1-3.
Expression pattern of Jagged2 gene in mandibular condylar cartilage was examined by means of in situ hybridization (ISH) technique. At E14, Jagged2 mRNA signals appeared in cytoplasm of proliferating chondrocytes. From E15 to E19, Jagged2 mRNA was detected throughout almost all cytoplasm in all layers. However, the distribution pattern was not uniform. These results suggest that Jagged2 plays an essential role for mandibular condylar cartilage morphogenesis and development.
采用原位杂交（ISH）技术检测锯齿状蛋白2（Jagged2）基因在下颌髁突软骨中的表达模式。在胚胎第14天（E14），Jagged2 mRNA信号出现在增殖软骨细胞的细胞质中。从E15到E19，Jagged2 mRNA在所有层的几乎所有细胞质中均有检测到。然而，其分布模式并不均匀。这些结果表明，Jagged2对下颌髁突软骨的形态发生和发育起着至关重要的作用。
Zotero 插件