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既往腹部手术后的腹腔镜肾上腺切除术。

Laparoscopic adrenalectomy after prior abdominal surgery.

作者信息

Morris Lilah, Ituarte Philip, Zarnegar Rasa, Duh Quan-Yang, Ahmed Leaque, Lee James, Inabnet William, Meyer-Rochow Goswin, Sidhu Stan, Sywak Mark, Yeh Michael

机构信息

Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA.

出版信息

World J Surg. 2008 May;32(5):897-903. doi: 10.1007/s00268-007-9438-z.

Abstract

BACKGROUND

Compared with the open procedure, laparoscopic adrenalectomy (LA) is associated with decreased operative time, perioperative complications, and hospital stay. Some regard prior abdominal surgery as a contraindication to LA or suggest a retroperitoneoscopic approach. We studied the effect of prior abdominal surgery on the feasibility and safety of transabdominal LA.

METHODS

We retrospectively analyzed 246 consecutive LAs performed at four academic centers from 2002 to 2006. Cases were grouped according to prior abdominal surgery (PAS) (n=92, 37%) or no prior surgery (NPS) (n=154, 63%). Statistical power was greater than 0.90 to detect the following differences in endpoints: conversion 2%, operating time 22%, and complications 2%.

RESULTS

Mean tumor size was 3.3 cm, 8.1% of tumors were larger than 7 cm, and 20% were pheochromocytomas. Prior operations were upper abdominal (37%), lower abdominal (48%), or laparoscopic (15%). There were nine conversions (3.7%), one in the PAS group and eight in the NPS group (p=0.14), with conversions related to large tumor size and pheochromocytoma (both p<0.01). Operating time was 158+/-59 min across groups. The subgroup with prior upper abdominal surgery had nonsignificantly longer operating times compared with the NPS group (183 vs. 165 min, p=0.16). Operative blood loss was 67+/-84 ml and the perioperative complication rate was 12.2%, with no differences between groups.

CONCLUSION

Prior abdominal surgery does not impede transabdominal LA. More than one-third of patients requiring adrenalectomy will have had prior abdominal surgery, and these patients should not be denied the benefits of a laparoscopic procedure.

摘要

背景

与开放手术相比,腹腔镜肾上腺切除术(LA)具有手术时间缩短、围手术期并发症减少及住院时间缩短等优点。一些人将既往腹部手术视为LA的禁忌证,或建议采用后腹腔镜入路。我们研究了既往腹部手术对经腹LA的可行性和安全性的影响。

方法

我们回顾性分析了2002年至2006年在四个学术中心连续进行的246例LA病例。根据既往腹部手术(PAS)情况(n = 92,37%)或无既往手术(NPS)情况(n = 154,63%)对病例进行分组。检测以下终点差异的统计效能大于0.90:中转率2%、手术时间22%和并发症2%。

结果

肿瘤平均大小为3.3 cm,8.1%的肿瘤大于7 cm,20%为嗜铬细胞瘤。既往手术为上腹部手术(37%)、下腹部手术(48%)或腹腔镜手术(15%)。共有9例中转(3.7%)——PAS组1例,NPS组8例(p = 0.14),中转与肿瘤体积大及嗜铬细胞瘤有关(均p < 0.01)。各组手术时间为158 ± 59分钟。与NPS组相比,既往有上腹部手术的亚组手术时间虽无显著延长(183分钟对165分钟,p = 0.16)。术中失血量为67 ± 84 ml,围手术期并发症发生率为12.2%,两组间无差异。

结论

既往腹部手术并不妨碍经腹LA。超过三分之一需要肾上腺切除术的患者会有既往腹部手术史,不应剥夺这些患者接受腹腔镜手术的益处。

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