细胞牵引力

Cell traction.

作者信息

Galbraith C G, Sheetz M P

机构信息

Duke University Medical Center, Durham, North Carolina, USA.

出版信息

Curr Protoc Cell Biol. 2001 May;Chapter 12:Unit 12.3. doi: 10.1002/0471143030.cb1203s00.

DOI:10.1002/0471143030.cb1203s00

PMID:18228317

Abstract

Traction forces are exerted by cells on their substratum as they migrate. These forces under the entire cell or subcellular regions can be measured. This unit describes several protocols for making silicone sheets to measure traction forces under the entire cell, as well as a protocol for developing a micromachined device to measure forces under subcellular regions.

摘要

细胞迁移时会对其基质施加牵引力。整个细胞或亚细胞区域下的这些力是可以测量的。本单元描述了几种制作硅树脂片以测量整个细胞下牵引力的方案，以及一种开发微机械装置以测量亚细胞区域下力的方案。