Christodoulides T, Dudley R, Brown S, Turkington D, Beck Aaron T
South of Tyne Early Intervention in Psychosis Service, Northumberland, Tyne and Wear Mental Health NHS Trust, Sunderland, UK.
Psychol Psychother. 2008 Jun;81(Pt 2):199-207. doi: 10.1348/147608308X278295. Epub 2008 Jan 29.
Cognitive behaviour therapy (CBT) as an adjunct to medication has been shown to improve symptom management in patients with schizophrenia. However, little is understood about the value of CBT for people who are not prescribed antipsychotic medication.
A post hoc case series design was used to examine the outcome data of three participants selected from a randomized controlled trial for CBT for schizophrenia. The participants were included if they had received CBT and were not prescribed antipsychotic medication during active treatment.
The three patients improved on outcome measures of psychopathology, depression, or negative symptoms, some to a clinically significant degree.
CBT is a feasible treatment for people with schizophrenia who are not prescribed antipsychotic medication. It may be a valuable alternative to medication in treating symptoms of schizophrenia.
认知行为疗法（CBT）作为药物治疗的辅助手段，已被证明可改善精神分裂症患者的症状管理。然而，对于未服用抗精神病药物的人而言，CBT的价值却鲜为人知。
采用事后病例系列设计，以检查从一项针对精神分裂症的CBT随机对照试验中选取的三名参与者的结果数据。如果参与者接受了CBT且在积极治疗期间未服用抗精神病药物，则将其纳入研究。
三名患者在精神病理学、抑郁或阴性症状的结果测量方面有所改善，其中一些改善达到了临床显著程度。
CBT对于未服用抗精神病药物的精神分裂症患者是一种可行的治疗方法。在治疗精神分裂症症状方面，它可能是药物治疗的一种有价值的替代方法。
