Balis E, Diacaki C, Tselioti P, Perimeni D, Vourli S, Vatopoulos A, Giamarellou H, Prekates A
Tzanio General Hospital of Piraeus. Greece.
J Chemother. 2007 Dec;19(6):703-8. doi: 10.1179/joc.2007.19.6.703.
We report the first two cases of community-acquired necrotizing pneumonia and bacteremia complicated by acute respiratory distress syndrome (ARDS) due to Panton-Valantine leukocidin-producing methicillin-resistant Staphylococcus aureus (MRSA-PVL) in Greece, together with a short literature review. Diagnosis was made by culture and broad spectrum PCR of respiratory secretions and blood. One patient received appropriate therapy and recovered fully. The other one died rapidly due to septic shock and life-threatening hemoptysis. Clinicians should be suspicious of community-acquired pneumonia due to MRSA-PVL strain, because rigorous microbiological diagnosis, early and appropriate therapy is essential for favorable outcome.
我们报告了希腊首例两例社区获得性坏死性肺炎和菌血症合并急性呼吸窘迫综合征（ARDS）的病例，病原体为产杀白细胞素的耐甲氧西林金黄色葡萄球菌（MRSA-PVL），并进行了简短的文献综述。通过呼吸道分泌物和血液的培养及广谱聚合酶链反应（PCR）进行诊断。一名患者接受了适当治疗并完全康复。另一名患者因感染性休克和危及生命的咯血迅速死亡。临床医生应怀疑由MRSA-PVL菌株引起的社区获得性肺炎，因为严格的微生物学诊断、早期和适当的治疗对于取得良好预后至关重要。
