头裂芽生菌引起的颈椎间盘炎。

Cervical spondylodiscitis caused by Blastoschizomyces capitatus.

作者信息

Mejdoubi M, Huynh A, Danho C, Boot B

机构信息

Dept. of Neuroradiology, Purpan University Hospital, Toulouse, France.

出版信息

Infection. 2009 Apr;37(2):153-5. doi: 10.1007/s15010-007-7081-0. Epub 2008 Jan 29.

DOI:10.1007/s15010-007-7081-0

PMID:18231719

Abstract

A 37-year-old woman, during her second remission of acute myeloid leukemia, presented with severe neck pain and cervico-brachial neuralgia. Investigation revealed a C5-C6 spondylodiscitis. A CT-guided anterior biopsy decompressed the mass, immediately alleviated the symptoms, and isolated a rare yeast: Blastoschizomyces capitatus. To our knowledge, only three cases of spondylodiscitis with this yeast have been described. Six months of voriconazole and liposomal amphotericin B treatment produced a complete resolution on CT and MRI imaging. However, the ongoing severe yeast infection prevented the planned bone marrow allograft.

摘要

一名37岁女性，在急性髓系白血病第二次缓解期，出现严重颈部疼痛和颈臂神经痛。检查发现C5 - C6椎间盘炎。CT引导下的前路活检对肿块进行减压，症状立即缓解，并分离出一种罕见的酵母菌：头裂殖酵母。据我们所知，仅有三例关于这种酵母菌引起的椎间盘炎的病例被报道。伏立康唑和脂质体两性霉素B治疗六个月后，CT和MRI成像显示完全缓解。然而，持续的严重酵母菌感染阻碍了计划中的骨髓同种异体移植。