Diug E, Gladum E, Gafiţanu E, Diug V, Eţco L, Trigubenco I, Vartanov V, Sifman E
Institutul de Medicină N. Testemiţanu, Chişinău.
Rev Med Chir Soc Med Nat Iasi. 1991 Jul-Dec;95(3-4):299-301.
The authors suggested a new method for preparing the delivery in patients with severe gestosis consisting of local applications of Enzaprost F hydrogel in association with the correction of arterial hypertension in relation with the hemodynamic type. Unlike the previous preparations, in the composition of the hydrogel with prostaglandin F2-alpha, polyvinylpyrrolidone is also included, thus increased adhesive properties and a slower release of prostaglandin resulting. The correction of arterial hypertension depending on the hemodynamic type provided rapid stabilization of patients' condition. The suggested method does not only decrease by 2.4 times the prenatal hospitalization but also reduces with 16.2% the frequency of abdominal delivery in this category of patients.
作者提出了一种针对重度妊娠中毒症患者的新分娩准备方法，该方法包括局部应用Enzaprost F水凝胶，并根据血流动力学类型对动脉高血压进行校正。与先前的制剂不同，在含有前列腺素F2-α的水凝胶成分中还包含聚乙烯吡咯烷酮，从而提高了粘附性能，并使前列腺素的释放更缓慢。根据血流动力学类型对动脉高血压进行校正可使患者病情迅速稳定。所建议的方法不仅使产前住院时间减少了2.4倍，而且使这类患者的剖宫产频率降低了16.2%。
