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[濒死期及复苏后恢复期大脑中氨的生成]

[Ammonia formation in the brain during dying and in the recovery period following resuscitation].

作者信息

Khachatrian S A, Papian A A

出版信息

Biull Eksp Biol Med. 1977 Jun;83(6):686-8.

PMID:18236
Abstract

Dynamics of some nitrogen metabolism indices in the brain of dogs during dying and post-resuscitation period was studied in experiments on dogs. Glutamine proved to serve as the main source of ammonium hydrate in the brain during dying and clinical death. In the reconstruction period after revival of the organism glutamine was converted into ammonium eliminator, and the main sources of ammoniogenesis were labile amide protein groups.

摘要

通过对狗进行实验,研究了狗在濒死期和复苏后期大脑中一些氮代谢指标的动态变化。结果表明,在濒死期和临床死亡期间,谷氨酰胺是大脑中氢氧化铵的主要来源。在机体复苏后的重建期,谷氨酰胺转化为氨清除剂,氨生成的主要来源是不稳定的酰胺蛋白基团。

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