Boddingius J
Cell Tissue Res. 1976 Jul 30;170(3):383-414. doi: 10.1007/BF00219419.
In nine cell types of the adenohypophysis in untreated adult rainbow trout, histologically different activity phases, seasonal changes in activity, and the relation between certain cell types and the interrenal gland, thyroid or gonads were investigated by light and, occasionally, by electron microscopy. Special attention was given to the effect of social rank on the synthetic activity in adenohypophysial cells of trout kept in small groups in which a social hierarchy with one (light) dominant and several (dark) submissives is established. Cell types in the rostral pars distalis were azocarminophil (I) or amphiphil (II). Proximal pars distalis cell types were slightly basophil (IV), orangeophil (V), strongly basophil (VI) or chromophobe (VII). In the pars intermedia, cell types were amphiphil (VIII) or very slightly basophil (IX). Type III was a non-secretory supporting (?) cell. Histologically different activity phases abounded in type IV cells, which mainly occurred in the proximal pars distalis but were also found dispersed in the rostral pars distalis, the pars intermedia and the neurohypophysis. Influences of social rank were pronounced in type IV cells. Phases with a high synthetic activity were exclusively found in submissive animals, phases with a low synthetic activity occurred in dominants. As a positive relation existed between type IV cell activity and the social rank dependent activity of the interrenal gland, it was suggested that type IV cells produce ACTH. In (dominant) male trout treated with DOCG or ACTH, colloid-containing type IV cell phases, reflecting accumulation of the secretory product, were found. This supported the earlier suggestion that ACTH in the trout is produced in the basophil type IV cells and not, as reported in the literature, in cells comparable to type II.
通过光学显微镜以及偶尔使用电子显微镜，对未经处理的成年虹鳟腺垂体的九种细胞类型进行了研究，包括组织学上不同的活动阶段、活动的季节性变化，以及某些细胞类型与肾上腺、甲状腺或性腺之间的关系。特别关注了社会等级对小群体饲养的虹鳟腺垂体细胞合成活性的影响，在这些小群体中建立了一种社会等级制度，其中有一只（浅色）占主导地位的鱼和几只（深色）顺从的鱼。远侧部前端的细胞类型为偶氮嗜色细胞（I）或兼性嗜色细胞（II）。远侧部近端的细胞类型为轻度嗜碱性细胞（IV）、嗜橙色细胞（V）、重度嗜碱性细胞（VI）或嫌色细胞（VII）。在中间部，细胞类型为兼性嗜色细胞（VIII）或非常轻度嗜碱性细胞（IX）。III型是一种非分泌性支持（？）细胞。组织学上不同的活动阶段在IV型细胞中大量存在，IV型细胞主要出现在远侧部近端，但也分散在远侧部前端、中间部和神经垂体中。社会等级对IV型细胞有显著影响。合成活性高的阶段仅在顺从的动物中发现，合成活性低的阶段出现在占主导地位的动物中。由于IV型细胞活性与肾上腺的社会等级依赖性活性之间存在正相关关系，因此推测IV型细胞产生促肾上腺皮质激素。在用脱氧皮质酮或促肾上腺皮质激素处理的（占主导地位的）雄性虹鳟中，发现了含有胶体的IV型细胞阶段，这反映了分泌产物的积累。这支持了早期的推测，即虹鳟中的促肾上腺皮质激素是由嗜碱性IV型细胞产生的，而不是如文献报道的那样由类似于II型的细胞产生。
