Ching C K, Lai C K, Poon W T, Wong Ernest N P, Yan W W, Chan Albert Y W, Mak Tony W L
Hospital Authority Toxicology Reference Laboratory, Princess Margaret Hospital, Laichikok, Hong Kong.
Hong Kong Med J. 2008 Feb;14(1):50-4.
The Hospital Authority Toxicology Reference Laboratory confirmed six cases of phenformin use, with or without complications, from July 2005 to November 2006. Two of the patients presented with potentially fatal phenformin-induced lactic acidosis. Phenformin was found (or suspected to be) adulterating Chinese proprietary medicine in five of the six cases. We report these six cases to highlight the underrecognised hazards posed by phenformin, a banned drug in Hong Kong.
医院管理局毒理学参考实验室确认了2005年7月至2006年11月期间6例使用苯乙双胍的病例,有无并发症情况均有。其中两名患者出现了可能致命的苯乙双胍诱发的乳酸性酸中毒。在6例病例中的5例里,发现(或怀疑)苯乙双胍被掺假到中成药中。我们报告这6例病例,以凸显苯乙双胍(一种在香港被禁用的药物)所带来的未得到充分认识的危害。