Fukui Toshiro, Mitsuyama Toshiyuki, Takaoka Makoto, Uchida Kazushige, Matsushita Mitsunobu, Okazaki Kazuichi
The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University, Moriguchi, Japan.
Intern Med. 2008;47(3):151-5. doi: 10.2169/internalmedicine.47.0334. Epub 2008 Feb 1.
In January 2007, an 80-year-old man was admitted to our hospital for treatment of a pancreatic tumor. He had been diagnosed with autoimmune pancreatitis (AIP) in December 2003 for which steroid therapy had induced remission. In November 2006, tumor marker levels rapidly increased, and the patient was suspected of having pancreatic cancer based on imaging studies. The diagnosis was later confirmed by endoscopic ultrasound-guided fine-needle aspiration biopsy. Distinguishing AIP from pancreatic cancer is crucial; however, few previous reports have described any cases of pancreatic cancer associated with AIP. While several reports have speculated on the prognosis of AIP, natural courses of the disease remain uncertain. This report emphasizes that AIP can coexist with cancer.
2007年1月,一名80岁男性因胰腺肿瘤入院治疗。他曾在2003年12月被诊断为自身免疫性胰腺炎(AIP),接受类固醇治疗后病情缓解。2006年11月,肿瘤标志物水平迅速升高,根据影像学检查怀疑该患者患有胰腺癌。后来通过内镜超声引导下细针穿刺活检确诊。区分AIP和胰腺癌至关重要;然而,此前很少有报告描述过与AIP相关的胰腺癌病例。虽然有几份报告推测了AIP的预后,但该疾病的自然病程仍不确定。本报告强调AIP可与癌症共存。