使用三维相位敏感反转恢复技术对用于脑深部电刺激的丘脑底核进行术前识别。
Preoperative identification of subthalamic nucleus for deep brain stimulation using three-dimensional phase sensitive inversion recovery technique.
作者信息
Ishimori Takashi, Nakano Satoru, Mori Yasutane, Seo Reiko, Togami Taro, Masada Tetsuya, Kusuhara Toshiaki, Ohkawa Motoomi, Nagao Seigo, Yamashita Yuichi, Sugiura Satoshi
机构信息
Department of Radiology, Faculty of Medicine, Kagawa University, Miki, Kita, Kagawa, Japan.
出版信息
Magn Reson Med Sci. 2007;6(4):225-9. doi: 10.2463/mrms.6.225.
PURPOSE
We assessed the feasibility of utilizing three-dimensional (3D) phase sensitive inversion recovery (IR) images for preoperatively determining deep brain stimulator position.
METHODS
We measured geometric distortion with a grid phantom and evaluated images of 3 volunteers to determine optimum imaging parameters for 3D phase sensitive IR.
RESULTS
Geometric distortion measured less than 1.0%. Respective inversion and recovery times, which provided high T(1) contrast between the subthalamic nucleus and adjacent tissue, were 200 and 4000 ms. In studies of 3 volunteers and 2 patients, the subthalamic nucleus was clearly depicted in 3D phase sensitive IR images. The measured coordinates of the subthalamic nucleus agreed well with those calculated by conventional estimation from midpoint of the anterior and posterior commissure.
CONCLUSION
Three-dimensional phase sensitive inversion recovery was useful in visualizing the subthalamic nucleus for effective deep brain stimulation.
目的
我们评估了利用三维（3D）相位敏感反转恢复（IR）图像术前确定深部脑刺激器位置的可行性。
方法
我们用网格模型测量几何畸变，并评估3名志愿者的图像以确定3D相位敏感IR的最佳成像参数。
结果
测量的几何畸变小于1.0%。在丘脑底核与相邻组织之间提供高T(1)对比度的各自反转时间和恢复时间分别为200和4000毫秒。在对3名志愿者和2名患者的研究中，丘脑底核在3D相位敏感IR图像中清晰可见。测量的丘脑底核坐标与通过前后连合中点的传统估计计算出的坐标非常吻合。
结论
三维相位敏感反转恢复对于有效深部脑刺激时可视化丘脑底核很有用。
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