Dear Rachel, Wilcken Nicholas, Shannon Jenny
Medical Oncology, Westmead and Nepean Hospitals, New South Wales.
Aust Fam Physician. 2008 Jan-Feb;37(1-2):45-9.
It has been known for some time that key genetic changes are the principle mechanism of cancer development. These changes lead to abnormalities in the signalling pathways of cells and result in unregulated cell growth, angiogenesis and metastasis.
一段时间以来，人们已经知道关键的基因变化是癌症发展的主要机制。这些变化导致细胞信号通路异常，进而导致细胞生长失控、血管生成和转移。
