Georgescu Eugen Florin, Vasile Ion, Ionescu Reanina
Filantropia University Hospital from Craiova, Department of Internal Medicine 2, University of Medicine and Pharmacy Craiova, Craiova 200136, Romania.
World J Gastroenterol. 2008 Feb 14;14(6):954-9. doi: 10.3748/wjg.14.954.
Intestinal pseudo-obstruction (IPO) either acute or chronic is a condition including features of intestinal ileus in absence of mechanical obstruction. Our paper presents such a rare case of idiopathic IPO in a 53-year-old male patient with recurrent episodes of pseudo-obstruction, which were successfully resolved by anticholinesterase agents, motilin agonists or colonic decompression. However, the patient finally underwent total colectomy. Huge colonic dilatation was identified intraoperatorily, while histology showed a neuropathic variant of chronic intestinal pseudo-obstruction. Etiologic mechanisms and current therapeutic methods are reviewed in this paper, which concludes that IPO is a condition in which conservative treatment usually fails. Total colectomy with ileoanal pouch may be the only solution in these situations.
急性或慢性的肠道假性梗阻（IPO）是一种在没有机械性梗阻情况下具有肠梗阻特征的病症。我们的论文介绍了这样一例罕见的特发性IPO病例，该病例为一名53岁男性患者，反复出现假性梗阻发作，通过抗胆碱酯酶药物、胃动素激动剂或结肠减压成功缓解。然而，该患者最终接受了全结肠切除术。术中发现巨大的结肠扩张，而组织学显示为慢性肠道假性梗阻的神经病变型。本文回顾了病因机制和当前的治疗方法，得出结论：IPO是一种保守治疗通常无效的病症。在这些情况下，带回肠肛管袋的全结肠切除术可能是唯一的解决办法。
