子痫前期作为晚年心血管疾病的一个风险因素：子痫前期问卷的验证
Preeclampsia as a risk factor for cardiovascular disease later in life: validation of a preeclampsia questionnaire.
作者信息
Diehl Courtenay L, Brost Brian C, Hogan Marie C, Elesber Ahmad A, Offord Keneth P, Turner Stephen T, Garovic Vesna D
机构信息
Division of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA.
出版信息
Am J Obstet Gynecol. 2008 May;198(5):e11-3. doi: 10.1016/j.ajog.2007.09.038. Epub 2008 Feb 1.
OBJECTIVE
This study was undertaken to validate a self-administered questionnaire in verifying the diagnosis of preeclampsia, eclampsia, or toxemia in a group of women with a greater than 20-year history of preeclampsia.
STUDY DESIGN
Questionnaires were mailed to a random sample of 144 women who received a diagnosis of any of these 3 conditions and 158 women who had normotensive pregnancies at Mayo Clinic, Rochester, Minnesota, from 1960-1979.
RESULTS
A previous diagnosis of preeclampsia, eclampsia, or toxemia was verified with 80% sensitivity and 96% specificity.
CONCLUSION
Our validated questionnaire may be a useful research tool in identifying women with a previous history of preeclampsia. Women with a history of preeclampsia had a higher prevalence of future hypertension than those with a history of normotensive pregnancy.
目的
本研究旨在验证一份自填式问卷，以核实一组有子痫前期病史超过20年的女性子痫前期、子痫或毒血症的诊断。
研究设计
向1960年至1979年在明尼苏达州罗切斯特市梅奥诊所被诊断患有这三种疾病中的任何一种的144名女性以及158名血压正常的孕妇随机样本邮寄问卷。
结果
子痫前期、子痫或毒血症的既往诊断敏感性为80%，特异性为96%。
结论
我们验证过的问卷可能是识别有子痫前期病史女性的有用研究工具。有子痫前期病史的女性未来患高血压的患病率高于有血压正常妊娠史的女性。
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