The Generation R Study Group, Erasmus Medical Centre, Rotterdam, The Netherlands.
J Clin Epidemiol. 2010 Aug;63(8):932-7. doi: 10.1016/j.jclinepi.2009.10.010. Epub 2010 Mar 2.
In this study, we assessed the validity of maternally self-reported history of preeclampsia.
This study was embedded in the Generation R Study, a population-based prospective cohort study. Data were obtained from prenatal questionnaires and one questionnaire obtained 2 months postpartum from the mother. All women who delivered in hospital and returned a 2-month postpartum questionnaire (n = 4,330) were selected.
Of the 4,330 women, 76 out of 152 (50%) women who self-reported preeclampsia appeared not to have had the disease according to the definition (International Society for the Study of Hypertension in Pregnancy). From the women who self-reported not to have experienced preeclampsia, 11 out of 4,178 (0.3%) had suffered from preeclampsia. Sensitivity and specificity were 0.87 and 0.98, respectively. Higher maternal education level and parity were associated with a better self-reported diagnosis of preeclampsia.
The validity of maternal-recall self-reported preeclampsia is moderate. The reduced self-reported preeclampsia might suggest a lack of accuracy in patient-doctor communication with regard to the diagnostic criteria of the disease. Therefore, doctors have to pay attention to make sure that women understand the nature of preeclampsia.
本研究旨在评估孕妇自我报告的子痫前期病史的有效性。
本研究嵌入了“生育队列研究”，这是一项基于人群的前瞻性队列研究。数据来自产前问卷和母亲产后 2 个月的一份问卷。所有在医院分娩并返回产后 2 个月问卷的女性（n=4330）都被选中。
在 4330 名女性中，152 名自我报告患有子痫前期的女性中，有 76 名（50%）根据定义（国际妊娠高血压学会）似乎并未患有该病。在自我报告未经历过子痫前期的女性中，有 4178 名中有 11 名（0.3%）患有子痫前期。敏感性和特异性分别为 0.87 和 0.98。较高的母亲教育水平和产次与更好的自我报告子痫前期诊断相关。
孕妇回忆自我报告子痫前期的有效性中等。自我报告子痫前期减少可能表明在与疾病诊断标准相关的医患沟通中缺乏准确性。因此，医生必须注意确保妇女了解子痫前期的性质。
