Solimene M C, Ramires J A, Gruppi C J, de Oliveira S F, da Luz P L, Pileggi F
Instituto do Coração do Hospital das Clínicas, FMUSP.
Arq Bras Cardiol. 1991 Nov;57(5):363-70.
To show a possible relation between heart rate and silent myocardial ischemia.
Forty-nine ischemic episodes were registered in six patients during a total period of 576-hour Holter monitoring. Those patients were selected from a group of 40 asymptomatic individuals after a first uncomplicated myocardial infarction; 11 (27.5%) showed ischemia during daily activities or exercise, the six selected patients had myocardial ischemia on Holter monitoring.
The silent episodes consisted 92% of the total ischemic burden; they lasted from 1 min 30 s to 20 min and the ST-segment depression varied from -1.1 mm to 3.3 mm. Thirty-five (72%) episodes occurred at rest or during light physical activities; nine (18.5%) occurred between 7:00 AM and 12:00 PM; eight (16.5%), between 12:00 PM and 6:00 PM; 17 (35%) between 6:00 PM and 12:00 AM and 15 (30%), between 12:00 AM and 7:00 AM. There was no significant change (more than 20%) in heart rate at the onset of ischemic episodes in relation to the heart rate 1 minute before (94.63 +/- 9.79 bpm and 99.47 +/- 10.99 bpm, respectively). Complex ventricular arrhythmias occurred in all patients and only one of them had an episode of nonsustained ventricular tachycardia related to silent ischemia.
Our results suggest that there is no relation between heart rate, arrhythmias and silent ischemia.
探讨心率与无症状性心肌缺血之间的可能关系。
在576小时的动态心电图监测期间,6例患者共记录到49次缺血发作。这些患者选自40例首次发生无并发症心肌梗死的无症状个体;其中11例(27.5%)在日常活动或运动时出现缺血,选取的6例患者在动态心电图监测时有心肌缺血。
无症状发作占总缺血负荷的92%;持续时间从1分30秒至20分钟,ST段压低幅度在-1.1毫米至3.3毫米之间。35次(72%)发作发生在休息时或轻度体力活动期间;9次(18.5%)发生在上午7:00至12:00之间;8次(16.5%)发生在下午12:00至6:00之间;17次(35%)发生在下午6:00至午夜12:00之间,15次(30%)发生在午夜12:00至上午7:00之间。缺血发作开始时的心率与发作前1分钟的心率相比无显著变化(超过20%)(分别为94.63±9.79次/分和99.47±10.99次/分)。所有患者均出现复杂性室性心律失常,其中只有1例有无症状缺血相关的非持续性室性心动过速发作。
我们的结果表明心率、心律失常与无症状缺血之间无关联。