du Toit Daniel F, Lambrechts Anton V, Stark Hugo, Warren Brian L
Department of Surgery, University of Stellenbosch, Tygerberg Hospital, Tygerberg, South Africa.
J Vasc Surg. 2008 Apr;47(4):739-43. doi: 10.1016/j.jvs.2007.11.009. Epub 2008 Feb 1.
The management of penetrating subclavian artery injuries poses a formidable surgical challenge. The feasibility of stent graft repair is already established. General use of this modality is not widely accepted due to concerns regarding the long-term outcome in a generally young patient population. We review our stent graft experience to examine long-term outcomes.
All patients with penetrating subclavian artery injuries were evaluated for stent graft repair. Patients were excluded when hemodynamically unstable or unsuitable on other clinical and angiographic grounds. Patients were followed prospectively for early (<30 days) and late (>30 days) complications. Clinical and telephone evaluation, Doppler pressures, duplex Doppler, and angiography (when indicated), were used to asses patients at follow-up. Outcomes were recorded as technical success of procedure, graft patency, arm claudication, limb loss, the need for open surgical repair, the presence or absence of other complications, and death.
Fifty-seven patients underwent stent graft treatment during the 10-year period. Mean age was 34, and 91% were men. There were 53 stab wounds and four gunshot injuries. Pathology included false aneurysms (n = 42), arteriovenous fistula (n = 12), and three arterial occlusions. Early complications: One patient (2%) had a femoral puncture site injury which was managed with open surgical repair. One patient died early due to multiple organ failure related to concomitant injuries. Three patients (5%) presented with graft occlusion and nonlimb threatening ischemia in the first week after treatment. All three patients were managed successfully with a second endovascular intervention. Late complications: Twenty-five (44%) of the 57 patients with subclavian artery injuries were followed-up with a mean duration of 48 months. Two patients died as a result of fatal stab wounds months after their first injuries. Five patients (20%) and three patients (12%) presented with angiographically significant stenosis and occlusions, respectively. The stenotic lesions were successfully managed with endovascular intervention, and the occluded lesions were managed conservatively. No patient experienced life or limb loss or any incapacitating symptoms at the end of the study period. There was no need for conversion to open surgery.
This study has reaffirmed the feasibility and safety of stent graft repair in treating stable patients with selected penetrating subclavian artery injuries. The results of this study also confirmed acceptable long-term follow-up without any limb or life threatening complications. We conclude that endovascular repair should be considered the first choice of treatment in stable patients with subclavian artery injuries.
锁骨下动脉穿透伤的治疗是一项艰巨的外科挑战。支架移植物修复的可行性已得到证实。由于担心该方法在一般年轻患者群体中的长期效果,这种治疗方式尚未被广泛接受。我们回顾了我们使用支架移植物的经验,以研究其长期效果。
对所有锁骨下动脉穿透伤患者进行支架移植物修复评估。血流动力学不稳定或因其他临床和血管造影原因不适合的患者被排除。对患者进行前瞻性随访,观察早期(<30天)和晚期(>30天)并发症。随访时采用临床和电话评估、多普勒压力测量、双功多普勒检查以及血管造影(必要时)来评估患者。记录的结果包括手术技术成功、移植物通畅、上肢间歇性跛行、肢体缺失、是否需要开放手术修复、是否存在其他并发症以及死亡情况。
在10年期间,57例患者接受了支架移植物治疗。平均年龄为34岁,91%为男性。有53处刺伤和4处枪伤。病理类型包括假性动脉瘤(n = 42)、动静脉瘘(n = 12)和3处动脉闭塞。早期并发症:1例患者(2%)出现股动脉穿刺部位损伤,通过开放手术修复处理。1例患者因与合并伤相关的多器官功能衰竭早期死亡。3例患者(5%)在治疗后第一周出现移植物闭塞和不危及肢体的缺血。所有3例患者通过第二次血管内介入治疗成功处理。晚期并发症:57例锁骨下动脉损伤患者中的25例(44%)接受了随访,平均随访时间为48个月。2例患者因初次受伤数月后致命刺伤死亡。分别有5例患者(20%)和3例患者(12%)出现血管造影显示的明显狭窄和闭塞。狭窄病变通过血管内介入治疗成功处理,闭塞病变采取保守治疗。在研究期末,没有患者出现生命或肢体丧失或任何致残症状。无需转为开放手术。
本研究再次证实了支架移植物修复治疗选定的稳定型锁骨下动脉穿透伤患者的可行性和安全性。本研究结果还证实了可接受的长期随访结果,无任何危及肢体或生命的并发症。我们得出结论,对于稳定型锁骨下动脉损伤患者,血管内修复应被视为首选治疗方法。