Hnatyszyn Grazyna, Cyryłowski Lech, Gizewska Maria, Kabacińska Anna, Konefał Halina, Jaroszewicz-Zrebiec Danuta
Department of Neonatology, Pomeranian Medical University, Poland.
Turk J Pediatr. 2007 Oct-Dec;49(4):426-30.
Magnetic resonance imaging (MRI) of the brain in preterm infants at term-equivalent age demonstrated that apart from cystic periventricular leukomalacia (PVL), noncystic white matter injury may take place, detected as diffuse excessive high signal intensity (DEHSI) in the white matter on T2-weighted imaging. Magnetic resonance imaging of the brain is conducted in few neonatal intensive care units. Consequently, the literature on the subject lacks descriptions of sequelae of noncystic white matter injury in premature newborns with very low birth weight (VLBW). We present the results of a three-year long observation of a child born at the 27th week of pregnancy diagnosed with DEHSI. The boy exhibited cerebral palsy, hyperexcitability and hypoacusis. In the authors' opinion, noncystic white matter injury may not just be one of the reasons for cognitive/behavioral deficits--it may also be responsible for some cases of cerebral palsy in premature infants.
对足月相当年龄的早产儿进行脑部磁共振成像（MRI）检查发现，除了囊性脑室周围白质软化（PVL）外，还可能发生非囊性白质损伤，在T2加权成像上表现为白质内弥漫性高信号强度（DEHSI）。很少有新生儿重症监护病房会对脑部进行磁共振成像检查。因此，关于极低出生体重（VLBW）早产儿非囊性白质损伤后遗症的文献报道较少。我们展示了对一名孕27周出生、诊断为DEHSI的儿童进行的为期三年的观察结果。该男孩表现出脑瘫、过度兴奋和听力减退。作者认为，非囊性白质损伤可能不仅是认知/行为缺陷的原因之一，还可能是一些早产儿脑瘫病例的病因。
