巴西巴伊亚州接受高效抗逆转录病毒疗法（HAART）的艾滋病病毒感染患者的口腔表现
Oral manifestations of HIV infection in patients receiving highly active antiretroviral therapy (HAART) in Bahia, Brazil.
作者信息
da Silva Carlos Alberto Lima, Dourado Inês, Dahia Samir Resack, Harzheim Erno, Rutherford George Williams
机构信息
Instituto de Saúde Coletiva, Universidade Federal de Bahia, Rua Basílio da Gama, S/N, CEP 40110-040 Campus do Canela, Salvador, Bahia, Brazil.
出版信息
J Public Health Dent. 2008 Summer;68(3):178-81. doi: 10.1111/j.1752-7325.2007.00071.x.
OBJECTIVES
We investigated the oral manifestations of HIV-infected patients in Salvador, Brazil, and their relationship to immunologic, sociodemographic, and therapeutic factors.
METHODS
This was a cross-sectional study that used data from adult patients' medical records in the dentistry service of the AIDS Reference Center in Salvador, Brazil. We reviewed the patients' records to collect information concerning oral health status and data on socioeconomic status, immunologic status, and treatment.
RESULTS
A total of 993 patients were included in the study, of whom 473 (47.6 percent) were male. Approximately 5.5 percent of the patients presented with any oral lesions. Oral lesions were the most common in the patients with fewer than 350 CD4+ T lymphocytes (8.4 percent) and with viral loads greater than 10,000 copies (8.3 percent).
CONCLUSIONS
Our study shows that lesions are more common in patients with advanced immune suppression and low level of schooling. Oral candidiasis and angular chelitis were the most common lesions seen.
目的
我们调查了巴西萨尔瓦多市艾滋病毒感染患者的口腔表现及其与免疫、社会人口统计学和治疗因素的关系。
方法
这是一项横断面研究，使用了巴西萨尔瓦多市艾滋病参考中心牙科服务中成年患者病历的数据。我们查阅患者记录以收集有关口腔健康状况的信息以及社会经济状况、免疫状况和治疗的数据。
结果
共有993名患者纳入研究，其中473名（47.6%）为男性。约5.5%的患者出现任何口腔病变。口腔病变在CD4+T淋巴细胞少于350个的患者中最为常见（8.4%），在病毒载量大于10000拷贝的患者中也较为常见（8.3%）。
结论
我们的研究表明，病变在免疫抑制严重和受教育程度低的患者中更为常见。口腔念珠菌病和口角炎是最常见的病变。
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