Vajdovich Peter
Department of Internal Medicine and Clinics, Szent István University, H-1078, István u. 2., P.O. Box 1400, Budapest, Hungary.
Vet Clin North Am Small Anim Pract. 2008 Jan;38(1):31-123, v. doi: 10.1016/j.cvsm.2007.11.008.
This article discusses the current understanding of the role of free radicals and antioxidants in inflammatory processes and in ischemia reperfusion injury. It begins by describing the manifestations of acute inflammation and outlining the cellular events that occur during inflammation. It then describes the biochemical mediators of inflammation with special attention to nitric oxide. It details the process of hypoxia reperfusion injury, the enzymes involved, its treatment, and studies involving specific hypoxia reperfusion injuries in various animal species.
本文讨论了目前对自由基和抗氧化剂在炎症过程及缺血再灌注损伤中作用的理解。文章开篇描述了急性炎症的表现，并概述了炎症过程中发生的细胞事件。接着描述了炎症的生化介质，特别关注一氧化氮。详细阐述了缺氧再灌注损伤的过程、涉及的酶、其治疗方法以及在各种动物物种中涉及特定缺氧再灌注损伤的研究。
