Harcos P, Márkus A, Péter A, Pucsok J
Eur Neurol. 1976;14(4):241-9. doi: 10.1159/000114746.
A case with central nervous symptoms in type V hyperlipoproteinemia was described. The 39-year-old male patient suffered from abdominal pains after fatty meals since childhood. After the age of 31 he developed attacks of cephaleas. Headaches were associated with vertigo, paresis and paresthesia of the limbs and loss of consciousness in some instances. During antilipemic treatment combined with a diet of restricted fat and carbohydrate content the patient became free of complaints. Authors emphasize the impairment of cerebral circulation and tissue hypoxia in the development of cerebral disturbances in hyperlipoproteinemia. The mechanism of the development of hypoxia is discussed.
本文描述了一例Ⅴ型高脂蛋白血症伴中枢神经症状的病例。该39岁男性患者自幼进食脂肪餐后即出现腹痛。31岁后开始出现头痛发作。头痛伴有眩晕、肢体轻瘫和感觉异常,有时还会出现意识丧失。在进行降脂治疗并配合低脂、低糖饮食后,患者症状消失。作者强调高脂蛋白血症时脑循环障碍和组织缺氧在脑部病变发生过程中的作用,并对缺氧的发生机制进行了讨论。