血管性痴呆

Vascular dementia.

作者信息

Schneck Michael J

机构信息

Neurology and Neurosurgery, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois, USA.

出版信息

Top Stroke Rehabil. 2008 Jan-Feb;15(1):22-6. doi: 10.1310/tsr1501-22.

DOI:10.1310/tsr1501-22

PMID:18250070

Abstract

Vascular dementia (VaD) is the second most common form of dementia after Alzheimer's dementia (AD). It is characterized by loss of executive function with milder memory loss as compared with AD and is associated with cerebral brain infarction or hemorrhage. Treatment is predominantly focused on cardiovascular risk factor reduction, but anticholinesterase inhibitors and memantine may play a role. The data is most robust for donepezil.

摘要

血管性痴呆（VaD）是仅次于阿尔茨海默病性痴呆（AD）的第二常见痴呆类型。其特征是执行功能丧失，与AD相比记忆丧失较轻，且与脑梗死或脑出血有关。治疗主要集中在降低心血管危险因素，但抗胆碱酯酶抑制剂和美金刚可能会发挥作用。多奈哌齐的数据最为充分。