Tomey Kristin M, Sowers Maryfran R, Crandall Carolyn, Johnston Janet, Jannausch Mary, Yosef Matheos
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Am J Epidemiol. 2008 Apr 15;167(8):935-43. doi: 10.1093/aje/kwm397. Epub 2008 Feb 3.
Physical functioning measures are considered integrated markers of the aging process. This prospective investigation examined relations between dietary intake of women at midlife in 1996-1997 and prevalence of physical functioning limitations 4 years later, defined by the Medical Outcomes Study Short-Form 36. The sample included 2,160 multiethnic women, aged 42-52 years, from six geographic areas participating in the Study of Women's Health Across the Nation (SWAN). Associations between measures of diet quality and number of fruit and vegetable servings and prevalent physical functional limitations (no, moderate, or substantial limitations) were tested by logistic regression. The prevalence of moderate and substantial functional limitations was 31% and 10%, respectively. Women in the highest quartile of cholesterol intake had 40% greater odds (odds ratio = 1.4, 95% confidence interval: 1.1, 1.8) of being more limited versus those in the lowest quartile. Women in the highest quartile of fat and saturated fat intakes were 50% and 60% more likely to be more limited, with respective odds ratios of 1.5 and 1.6 (95% confidence intervals: 1.2, 2.0 and 1.2, 2.1) versus those in the lowest quartiles. Lower fruit, vegetable, and fiber intakes were related to reporting greater functional limitations. Modifying dietary practices could be important in minimizing physical limitations.
身体功能指标被视为衰老过程的综合标志。这项前瞻性调查研究了1996 - 1997年中年女性的饮食摄入量与4年后身体功能受限患病率之间的关系,身体功能受限情况由医学结局研究简表36进行定义。样本包括来自参与全国女性健康研究(SWAN)的六个地理区域的2160名多民族女性,年龄在42 - 52岁之间。通过逻辑回归分析了饮食质量指标、水果和蔬菜摄入量与普遍存在的身体功能受限(无、中度或重度受限)之间的关联。中度和重度功能受限的患病率分别为31%和10%。胆固醇摄入量处于最高四分位数的女性比处于最低四分位数的女性功能受限程度更高的几率高40%(优势比 = 1.4,95%置信区间:1.1,1.8)。脂肪和饱和脂肪摄入量处于最高四分位数的女性功能受限程度更高的可能性分别比处于最低四分位数的女性高50%和60%,优势比分别为1.5和1.6(95%置信区间:1.2,2.0和1.2,2.1)。水果、蔬菜和纤维摄入量较低与报告的功能受限程度较高有关。改变饮食习惯对于尽量减少身体受限可能很重要。