Creugers N H, Van 't Hof M A
Department of Oral Function and Prosthetic Dentistry, Dental School, Nijmegen, The Netherlands.
J Dent Res. 1991 Feb;70(2):146-9. doi: 10.1177/00220345910700021001.
Many clinical data on resin-bonded bridges (RBBs) have been published in the last ten years. The survival rates vary widely, and the conclusions are sometimes conflicting. A method of combining the results of different studies in order to draw conclusions about the effectiveness of therapeutic concepts is meta-analysis. The aims of the meta-analysis in this study were: (1) to assess an "overall" survival ratio for RBBs and (2) to explore relationships between potential success factors and reported survival times. About 60 publications with clinical data on RBBs were reviewed. Following a number of inclusion criteria (information adequate to calculate or assess survival rates, as well as adequate information about the patients, the designs, and types of RBBs), 16 different samples were used for this meta-analysis. A weighted multiple-regression analysis revealed no significant effects of "type of retention" and "location" on the survival percentages. Kaplan-Meier estimates were used to assess overall survival in a secondary analysis with the data from all 16 samples (n = 1598). The overall survivals were: one year, 89 +/- 1%; two years, 84 +/- 1%; three years, 80 +/- 1%; and four years, 74 +/- 2%.
在过去十年中，已经发表了许多关于树脂粘结桥（RBBs）的临床数据。其生存率差异很大，结论有时相互矛盾。为了得出关于治疗概念有效性的结论而合并不同研究结果的方法是荟萃分析。本研究中荟萃分析的目的是：（1）评估RBBs的“总体”生存率，以及（2）探索潜在成功因素与报告的生存时间之间的关系。对约60篇包含RBBs临床数据的出版物进行了综述。根据一些纳入标准（有足够信息来计算或评估生存率，以及关于患者、RBBs的设计和类型的足够信息），本荟萃分析使用了16个不同的样本。加权多元回归分析显示“固位类型”和“位置”对生存百分比没有显著影响。在二次分析中，使用Kaplan-Meier估计法对所有16个样本（n = 1598）的数据进行总体生存评估。总体生存率为：一年，89±1%；两年，84±1%；三年，80±1%；四年，74±2%。
