Horvath Balazs, Yang Mingxue, Manning Frank A
Department of Obstetrics and Gynecology, New York University Downtown Hospital, 170 William Street, New York, NY 10038, USA.
J Reprod Med. 2008 Jan;53(1):55-6.
Haemophilus influenzae is a rare cause of intrauterine infection, with the potential to cause severe morbidity and mortality in the perinate.
An 18-year-old primigravida presented at 32 weeks' gestation with sudden-onset abdominal pain and abrupt cessation of fetal movements. Intrauterine fetal death was confirmed. At necropsy the fetus had multiorgan hemorrhage. H influenzae was cultured from the amniotic membranes and ear canal fluid. The mother was readmitted on postpartum day 2 with fever. Her blood cultures were also positive for H influenzae.
H influenzae may cause ascending fetal infection and death and may cause maternal sepsis by fetomaternal transmission.
流感嗜血杆菌是宫内感染的罕见病因,有可能导致围产儿出现严重发病和死亡。
一名18岁初产妇在妊娠32周时出现突发腹痛和胎动突然停止。确诊为宫内胎儿死亡。尸检发现胎儿有多器官出血。在羊膜和耳道液中培养出流感嗜血杆菌。母亲在产后第2天因发热再次入院。她的血培养结果也显示流感嗜血杆菌呈阳性。
流感嗜血杆菌可能导致上行性胎儿感染和死亡,并可能通过母婴传播导致产妇败血症。