Zarnowska Hanna, Borecka Anna, Gawor Jakub, Marczyńska Magdalena, Dobosz Sabina, Basiak Wojciech
Department of Zoonoses and Tropical Diseases, Medical University of Warsaw, Poland.
J Helminthol. 2008 Jun;82(2):123-7. doi: 10.1017/S0022149X08912372. Epub 2008 Feb 5.
The level of specific anti-Toxocara IgG was examined in 343 children from central Poland with suspected Toxocara infection. Based on the presence of specific IgG antibodies and clinical signs and symptoms, toxocariasis was confirmed in 249 patients. The serological results of diagnosed cases were analysed in connection with epidemiological data (contamination of soil around the children's homes and presence of a dog or a cat). A higher prevalence of soil contamination with Toxocara eggs was found in suburban and rural areas (30.9% and 24.6%, respectively) whereas it was lower in urban areas (10.3%). In about 40% of the children whose households were not contaminated, a decrease in the antibody level was observed 2 years after treatment for toxocariasis, while there was no such decline in those living in contaminated places. The logistic regression model employed to determine the correlation between seropositivity in the children and selected epidemiological risk factors showed a statistically significant relationship in connection only with dog ownership (P = 0.0238). The present results have demonstrated the high risk of toxocariasis for children from rural and suburban areas in Poland. The sero-epidemiological investigations indicated that re-infection might be the reason for persistence of seropositivity after treatment.
对来自波兰中部343名疑似弓蛔虫感染的儿童检测了特异性抗弓蛔虫IgG水平。根据特异性IgG抗体的存在情况以及临床症状和体征，确诊249例弓蛔虫病患者。结合流行病学数据（儿童家庭周围土壤污染情况以及是否养猫或狗）对确诊病例的血清学结果进行了分析。在郊区和农村地区发现土壤被弓蛔虫卵污染的比例较高（分别为30.9%和24.6%），而在城市地区较低（10.3%）。在约40%家庭未受污染的儿童中，治疗弓蛔虫病2年后观察到抗体水平下降，而生活在受污染地区的儿童则没有这种下降。用于确定儿童血清阳性与选定流行病学危险因素之间相关性的逻辑回归模型显示，仅与养狗存在统计学显著关系（P = 0.0238）。目前的结果表明波兰农村和郊区儿童感染弓蛔虫病的风险很高。血清流行病学调查表明，再次感染可能是治疗后血清阳性持续存在的原因。
