Kala Jaya, Sahay Sandeep, Shah Ashok
Department of Respiratory Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, India.
Prim Care Respir J. 2008 Mar;17(1):51-5. doi: 10.3132/pcrj.2008.00003.
Bronchial anthracofibrosis, a clinical entity described less than a decade ago, is characterised by anthracotic pigmentation of the bronchial mucosa with multifocal bronchial lumen narrowing. The right middle lobe is predominantly involved and is frequently associated with tuberculosis. The condition is generally seen in non-smoking elderly ladies with a longstanding history of wood smoke exposure. A 65 year-old lady presented to us with a one-month history of dry cough. The chest radiograph revealed a middle lobe syndrome which was confirmed on computed tomography (CT) scanning. In addition, narrowing of the right middle lobe bronchus was seen. This raised the suspicion of a malignancy. Fibreoptic bronchoscopy revealed anthracotic pigmentation, and bronchial aspirate showed acid fast bacilli. Culture of the aspirate grew Mycobacterium tuberculosis. The patient responded to standard antituberculous treatment.
支气管煤尘纤维变性是一种不到十年前才被描述的临床病症,其特征为支气管黏膜出现煤尘色素沉着以及多灶性支气管腔狭窄。右中叶受累最为常见,且常与肺结核相关。这种病症通常见于有长期接触木烟史的不吸烟老年女性。一位65岁女性因干咳1个月前来就诊。胸部X线片显示中叶综合征,计算机断层扫描(CT)证实了这一情况。此外,还可见右中叶支气管狭窄。这引发了对恶性肿瘤的怀疑。纤维支气管镜检查显示有煤尘色素沉着,支气管吸出物显示抗酸杆菌。吸出物培养出结核分枝杆菌。患者对标准抗结核治疗有反应。