Handoll H H G, Huntley J S, Madhok R
Royal Infirmary of Edinburgh, c/o University Department of Orthopaedic Surgery, Old Dalkeith Road, Little France, Edinburgh, UK, EH16 4SU.
Cochrane Database Syst Rev. 2008 Jan 23;2008(1):CD006522. doi: 10.1002/14651858.CD006522.pub2.
Fracture of the distal radius is a common injury. A surgical treatment is external fixation, where metal pins inserted into bone on either side of the fracture are then fixed to an external frame.
To evaluate the evidence from randomised controlled trials comparing different methods of external fixation for distal radial fractures in adults.
We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (June 2007), the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and other databases, conference proceedings and reference lists of articles. No language restrictions were applied.
Randomised or quasi-randomised controlled clinical trials which compared different methods of external fixation in adults with a distal radial fracture.
All review authors independently performed study selection. Two authors independently assessed the included trials and performed data extraction.
Nine small trials involving 510 adults with potentially or evidently unstable fractures, were grouped into five comparisons. The interventional, clinical and methodological heterogeneity of trials precluded data pooling. Only one trial had secure allocation concealment. Two trials comparing a bridging (of the wrist) external fixator versus pins and plaster external fixation found no significant differences in function or deformity. One trial found tendencies for more serious complications but less subsequent discomfort and deformity in the fixator group. Three trials compared non-bridging versus bridging fixation. Of the two trials testing uni-planar non-bridging fixation, one found no significant differences in functional or clinical outcomes; the other found non-bridging fixation significantly improved grip strength, wrist flexion and anatomical outcome. The third trial found no significant findings in favour of multi-planar non-bridging fixation of complex intra-articular fractures. One trial using a bridging external fixator found that deploying an extra external fixator pin to fix the 'floating' distal fragment gave superior functional and anatomical results. One trial found no evidence of differences in clinical outcomes for hydroxyapatite coated pins compared with standard uncoated pins. Two trials compared dynamic versus static external fixation. One trial found no significant effects from early dynamism of an external fixator. The poor quality of the other trial undermines its findings of poorer functional and anatomical outcomes for dynamic fixation.
AUTHORS' CONCLUSIONS: There is insufficient robust evidence to determine the relative effects of different methods of external fixation. Adequately powered studies could provide better evidence.
桡骨远端骨折是一种常见损伤。手术治疗方法为外固定,即将金属针插入骨折两侧的骨骼,然后固定到外部框架上。
评估比较成人桡骨远端骨折不同外固定方法的随机对照试验证据。
我们检索了Cochrane骨、关节和肌肉创伤组专业注册库(2007年6月)、Cochrane对照试验中心注册库、MEDLINE、EMBASE及其他数据库、会议论文集和文章参考文献列表。未设语言限制。
比较成人桡骨远端骨折不同外固定方法的随机或半随机对照临床试验。
所有综述作者独立进行研究选择。两位作者独立评估纳入试验并进行数据提取。
9项涉及510例有潜在或明显不稳定骨折成人的小型试验被分为5组比较。试验的干预、临床和方法学异质性使得无法进行数据合并。只有1项试验有可靠的分配隐藏。两项比较(跨越腕部的)桥式外固定器与针加石膏外固定的试验发现,功能或畸形方面无显著差异。一项试验发现固定器组有更严重并发症的趋势,但后续不适和畸形较少。三项试验比较了非桥式与桥式固定。在两项测试单平面非桥式固定的试验中,一项发现功能或临床结果无显著差异;另一项发现非桥式固定显著提高握力、腕关节屈曲和解剖学结果。第三项试验未发现支持复杂关节内骨折多平面非桥式固定的显著结果。一项使用桥式外固定器的试验发现,额外使用一根外固定针固定“浮动”的远端骨折块可获得更好的功能和解剖学结果。一项试验未发现羟基磷灰石涂层针与标准未涂层针在临床结果上有差异的证据。两项试验比较了动态与静态外固定。一项试验发现外固定器早期动态化无显著效果。另一项试验质量较差,削弱了其关于动态固定功能和解剖学结果较差的研究结果。
没有足够有力的证据来确定不同外固定方法的相对效果。有足够样本量的研究可以提供更好的证据。