Suppr超能文献

成人桡骨远端骨折的外固定与保守治疗对比

External fixation versus conservative treatment for distal radial fractures in adults.

作者信息

Handoll H H G, Huntley J S, Madhok R

机构信息

Royal Infirmary of Edinburgh, c/o University Department of Orthopaedic Surgery, Old Dalkeith Road, Little France, Edinburgh, UK, EH16 4SU.

出版信息

Cochrane Database Syst Rev. 2007 Jul 18(3):CD006194. doi: 10.1002/14651858.CD006194.pub2.

Abstract

BACKGROUND

Fracture of the distal radius ('broken wrist') is a common clinical problem. It can be treated conservatively, usually involving wrist immobilisation in a plaster cast, or surgically. A key method of surgical fixation is external fixation.

OBJECTIVES

To evaluate the evidence from randomised controlled trials comparing external fixation with conservative treatment for fractures of the distal radius in adults.

SEARCH STRATEGY

We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (September 2006), the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and other databases, conference proceedings and reference lists of articles. No language restrictions were applied.

SELECTION CRITERIA

Randomised or quasi-randomised controlled clinical trials involving adults with a fracture of the distal radius, which compared external fixation with conservative treatment.

DATA COLLECTION AND ANALYSIS

After independent study selection by all review authors, two authors independently assessed the included trials. Independent data extraction of new trials was performed by two authors. Pooling of data was undertaken where appropriate.

MAIN RESULTS

Fifteen heterogeneous trials, involving 1022 adults with dorsally displaced and potentially or evidently unstable distal radial fractures, were included. While all trials compared external fixation versus plaster cast immobilisation, there was considerable variation especially in terms of patient characteristics and interventions. Methodological weaknesses among these trials included lack of allocation concealment and inadequate outcome assessment. External fixation maintained reduced fracture positions (redisplacement requiring secondary treatment: 7/356 versus 51/338 (data from 9 trials); relative risk 0.17, 95% confidence interval 0.09 to 0.32) and prevented late collapse and malunion compared with plaster cast immobilisation. There was insufficient evidence to confirm a superior overall functional or clinical result for the external fixation group. External fixation was associated with a high number of complications, such as pin-track infection, but many of these were minor. Probably, some complications could have been avoided using a different surgical technique for pin insertion. There was insufficient evidence to establish a difference between the two groups in serious complications such as reflex sympathetic dystropy: 25/384 versus 17/347 (data from 11 trials); relative risk 1.31, 95% confidence interval 0.74 to 2.32.

AUTHORS' CONCLUSIONS: There is some evidence to support the use of external fixation for dorsally displaced fractures of the distal radius in adults. Though there is insufficient evidence to confirm a better functional outcome, external fixation reduces redisplacement, gives improved anatomical results and most of the excess surgically-related complications are minor.

摘要

背景

桡骨远端骨折(“手腕骨折”)是常见的临床问题。可采用保守治疗,通常是用石膏固定手腕,也可进行手术治疗。手术固定的一种关键方法是外固定。

目的

评估比较外固定与保守治疗成人桡骨远端骨折的随机对照试验证据。

检索策略

我们检索了Cochrane骨、关节和肌肉创伤组专业注册库(2006年9月)、Cochrane对照试验中央注册库、MEDLINE、EMBASE及其他数据库、会议论文集和文章参考文献列表。未设语言限制。

选择标准

涉及成人桡骨远端骨折的随机或半随机对照临床试验,比较外固定与保守治疗。

数据收集与分析

所有综述作者独立进行研究选择后,两位作者独立评估纳入试验。两位作者独立提取新试验的数据。在适当情况下进行数据合并。

主要结果

纳入15项异质性试验,涉及1022例背侧移位且可能或明显不稳定的桡骨远端骨折成人患者。虽然所有试验均比较了外固定与石膏固定,但在患者特征和干预措施方面存在很大差异。这些试验的方法学缺陷包括缺乏分配隐藏和结局评估不充分。与石膏固定相比,外固定能维持骨折复位位置(需要二次治疗的再移位:7/356对51/338(来自9项试验的数据);相对危险度0.17,95%置信区间0.09至0.32),并防止晚期塌陷和畸形愈合。没有足够证据证实外固定组在总体功能或临床结果方面更优。外固定与大量并发症相关,如针道感染,但其中许多为轻微并发症。可能采用不同的针插入手术技术可避免一些并发症。没有足够证据表明两组在诸如反射性交感神经营养不良等严重并发症方面存在差异:25/384对17/347(来自11项试验的数据);相对危险度1.31,95%置信区间0.74至2.32。

作者结论

有一些证据支持对成人桡骨远端背侧移位骨折采用外固定。虽然没有足够证据证实功能结局更好,但外固定可减少再移位,改善解剖结果,且大多数额外的手术相关并发症为轻微并发症。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验