Ukaga C N, Orji C N, Orogwu S, Nwoke B E B, Anosike J C, Udujih O S, Onyeka P I K, Awujo N C
Imo State University, Department of Animal and Environmental Biology, Oweri, Nigeria.
Tanzan Health Res Bull. 2006 Sep;8(3):186-8. doi: 10.4314/thrb.v8i3.45119.
The presence of concomitant bacteria was assessed in the blood of 125 malaria positive patients and 60 malaria negative controls, resident in Owerri, southeastern Nigeria. Blood samples were cultured in MacConkey, Chocolate and Blood agar, respectively using oxoid signal system after the manufacturer's instructions. Blood cultures of 44 (35.2%) of the 125 malaria positive patients had bacterial growth while none was observed in the blood cultures of malaria negative patients. The bacteria species identified included: Staphylococcus aureus 4 (3.2%), Escherichia coli 3 (2.4%) Salmonella typhi 25 (20%), Klebsiella pneumoniae 10 (2.4%) and Pseudomonas aeruginosa 2 (1.6%). The presence of concomitant bacteria in malaria-positive cases usually results in persistence of malaria-like symptoms after treatment with antimalarials and subsequently taken as resistance of the parasites to the particular drugs in question. The significance of concomitant bacteria in the management of malaria should be given priority.
在尼日利亚东南部奥韦里居住的125名疟疾阳性患者和60名疟疾阴性对照者的血液中评估了合并细菌的存在情况。按照制造商的说明,分别使用奥克托信号系统在麦康凯、巧克力和血琼脂中培养血样。125名疟疾阳性患者中有44名(35.2%)血培养有细菌生长,而疟疾阴性患者的血培养未观察到细菌生长。鉴定出的细菌种类包括:金黄色葡萄球菌4株(3.2%)、大肠杆菌3株(2.4%)、伤寒沙门氏菌25株(20%)、肺炎克雷伯菌10株(2.4%)和铜绿假单胞菌2株(1.6%)。疟疾阳性病例中合并细菌的存在通常导致用抗疟药治疗后疟疾样症状持续存在,随后被视为寄生虫对所讨论的特定药物耐药。合并细菌在疟疾管理中的意义应得到优先考虑。