Ray Camille Le, Lacerte Maxime, Iglesias Marie-Hélène, Audibert François, Morin Lucie
Department of Obstetrics and Gynecology, CHU Sainte Justine, University of Montreal, Montreal QC; INSERM Unit 149, Epidemiological Research Unit on Perinatal Health and Women's Health, Paris, France.
Department of Obstetrics and Gynecology, CHU Sainte Justine, University of Montreal, Montreal QC.
J Obstet Gynaecol Can. 2008 Feb;30(2):118-122. doi: 10.1016/S1701-2163(16)32734-7.
Policies for routine third trimester obstetrical ultrasound examinations differ among countries. In Canada, a routine third trimester ultrasound scan is not offered in the low-risk pregnancy population. This practice is based mainly on results of a meta-analysis published in 2001 that concluded "routine late pregnancy ultrasound in low-risk or unselected populations does not confer benefit on mother or baby." We reviewed in detail each study included in this meta-analysis in order to re-evaluate the Canadian practice regarding routine third trimester ultrasound in the low-risk pregnant population. The meta-analysis included outdated techniques and ultrasound examinations performed in the late 1970s and early 1980s. To assess the effect of routine third trimester ultrasound on perinatal outcome, the interventions prompted by an abnormal diagnostic test result must be considered. None of the trials included in the meta-analysis evaluated the effect of routine third trimester ultrasound on perinatal outcomes in a low-risk population when ultrasound assessment was followed by an altered perinatal management plan. Our assessment of the published evidence regarding routine third trimester ultrasound puts in question the contemporary validity of the conclusion of the 2001 meta-analysis. In fact, the 2001 meta-analysis has recently been withdrawn by the authors.
各国关于孕晚期常规产科超声检查的政策有所不同。在加拿大,低风险妊娠人群不进行常规孕晚期超声扫描。这种做法主要基于2001年发表的一项荟萃分析结果,该分析得出结论:“在低风险或未经过筛选的人群中进行常规晚期妊娠超声检查对母亲或婴儿没有益处。”我们详细回顾了该荟萃分析中包含的每项研究,以便重新评估加拿大在低风险妊娠人群中进行常规孕晚期超声检查的做法。该荟萃分析纳入了20世纪70年代末和80年代初使用的过时技术及超声检查。为评估常规孕晚期超声对围产期结局的影响,必须考虑由异常诊断检查结果引发的干预措施。该荟萃分析中纳入的试验均未评估在超声评估后采用改变的围产期管理计划时,常规孕晚期超声对低风险人群围产期结局的影响。我们对已发表的关于常规孕晚期超声的证据评估对2001年荟萃分析结论的当代有效性提出了质疑。事实上,2001年的荟萃分析最近已被作者撤回。