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Melanoma complicating treatment with natalizumab for multiple sclerosis.

作者信息

Mullen John T, Vartanian Timothy K, Atkins Michael B

出版信息

N Engl J Med. 2008 Feb 7;358(6):647-8. doi: 10.1056/NEJMc0706103.

DOI:10.1056/NEJMc0706103
PMID:18256405
Abstract
摘要

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Melanoma complicating treatment with natalizumab for multiple sclerosis.黑色素瘤使那他珠单抗治疗多发性硬化症变得复杂。
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Melanoma complicating treatment with natalizumab (tysabri) for multiple sclerosis.
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More on melanoma with transdifferentiation.更多关于伴有转分化的黑色素瘤的内容。
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Evolution of nevi during treatment with natalizumab: A prospective follow-up of patients treated with natalizumab for multiple sclerosis.那他珠单抗治疗期间痣的演变:对接受那他珠单抗治疗的多发性硬化症患者的前瞻性随访。
Arch Dermatol. 2011 Jan;147(1):72-6. doi: 10.1001/archdermatol.2010.243. Epub 2010 Sep 20.
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Natalizumab.那他珠单抗
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Natalizumab treatment in paediatric multiple sclerosis: a case of induction, de-escalation and escalation.那他珠单抗治疗儿童多发性硬化症:一例诱导、降阶梯及升阶梯治疗的病例
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Natalizumab and the role of alpha 4-integrin antagonism in the treatment of multiple sclerosis.那他珠单抗及α4整合素拮抗作用在多发性硬化治疗中的作用
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[Natalizumab: an antibody targeting α4-integrin].那他珠单抗:一种靶向α4整合素的抗体
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[Treatment of multiple sclerosis with natalizumab (Tysabri) in a setting of melanoma].
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The use of natalizumab for treatment of MS: do the risks still outweigh the gains?那他珠单抗用于治疗多发性硬化症:风险仍大于收益吗?
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Therapeutic targeting of anoikis resistance in cutaneous melanoma metastasis.皮肤黑色素瘤转移中失巢凋亡抗性的治疗靶点
Front Cell Dev Biol. 2023 Apr 26;11:1183328. doi: 10.3389/fcell.2023.1183328. eCollection 2023.
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Multiple Sclerosis Treatment and Melanoma Development.多发性硬化症的治疗与黑色素瘤的发展。
Int J Mol Sci. 2020 Apr 22;21(8):2950. doi: 10.3390/ijms21082950.
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VLA-4 phosphorylation during tumor and immune cell migration relies on its coupling to VEGFR2 and CXCR4 by syndecan-1.VLA-4 磷酸化在肿瘤和免疫细胞迁移过程中依赖于其通过 syndecan-1 与 VEGFR2 和 CXCR4 的偶联。
J Cell Sci. 2019 Oct 28;132(20):jcs232645. doi: 10.1242/jcs.232645.
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Rapid Progression of Low-Grade Cervical Dysplasia into Invasive Cancer during Natalizumab Treatment for Relapsing Remitting Multiple Sclerosis.在使用那他珠单抗治疗复发缓解型多发性硬化症期间,低度宫颈发育异常迅速进展为浸润性癌。
Case Rep Oncol. 2019 Jan 18;12(1):59-62. doi: 10.1159/000496198. eCollection 2019 Jan-Apr.
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Monoclonal Antibodies in Multiple Sclerosis: Present and Future.多发性硬化症中的单克隆抗体:现状与未来
Biomedicines. 2019 Mar 14;7(1):20. doi: 10.3390/biomedicines7010020.
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Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma.整合素作为人类恶性黑色素瘤器官特异性转移的治疗靶点。
J Exp Clin Cancer Res. 2018 Apr 27;37(1):92. doi: 10.1186/s13046-018-0763-x.
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Efficacy of alemtuzumab and natalizumab in the treatment of different stages of multiple sclerosis patients.阿仑单抗和那他珠单抗治疗不同阶段多发性硬化症患者的疗效。
Medicine (Baltimore). 2018 Feb;97(8):e9908. doi: 10.1097/MD.0000000000009908.
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K3.1 channel inhibition leads to an ICAM-1 dependent increase of cell-cell adhesion between A549 lung cancer and HMEC-1 endothelial cells.K3.1通道抑制导致A549肺癌细胞与HMEC-1内皮细胞之间的细胞间黏附以细胞间黏附分子-1(ICAM-1)依赖的方式增加。
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Glioblastoma in natalizumab-treated multiple sclerosis patients.那他珠单抗治疗的多发性硬化症患者中的胶质母细胞瘤
Ann Clin Transl Neurol. 2017 Jun 6;4(7):512-516. doi: 10.1002/acn3.428. eCollection 2017 Jul.
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Melanoma complicating treatment with natalizumab for multiple sclerosis: A report from the Southern Network on Adverse Reactions (SONAR).黑色素瘤使那他珠单抗治疗多发性硬化症变得复杂:南方不良反应网络(SONAR)的一份报告。
Cancer Med. 2017 Jul;6(7):1541-1551. doi: 10.1002/cam4.1098. Epub 2017 Jun 20.