霍乱毒素对垂体切除大鼠肾上腺重量的影响。
The effects of cholera toxin on the adrenal weight in hypophysectomized rats.
作者信息
Marton J, Palfreyman J W, Schulster D
出版信息
Mol Cell Endocrinol. 1976 Jun-Jul;5(1-2):147-9. doi: 10.1016/0303-7207(76)90077-0.
PMID:182572
Abstract
The effects of cholera on adrenal weight in hypophysectomized rats were investigated, in an attempt to demonstrate an ACTH-like, adrenal trophic effect of the toxin. The results suggested that the toxin probably exerts is ACTH-like action on the adrenal via adenylate cyclase. Cholera toxin was also shown to have a thermolytic action, similar to that of ACTH, probably due to stimulation of adrenal glucocorticoid secretion.
摘要
研究了霍乱对垂体切除大鼠肾上腺重量的影响，以试图证明该毒素具有促肾上腺皮质激素（ACTH）样的肾上腺营养作用。结果表明，该毒素可能通过腺苷酸环化酶对肾上腺发挥其ACTH样作用。霍乱毒素还显示出具有与ACTH类似的热分解作用，这可能是由于刺激了肾上腺糖皮质激素的分泌。
相似文献
1
The effects of cholera toxin on the adrenal weight in hypophysectomized rats.霍乱毒素对垂体切除大鼠肾上腺重量的影响。
Mol Cell Endocrinol. 1976 Jun-Jul;5(1-2):147-9. doi: 10.1016/0303-7207(76)90077-0.
2
Influence of time factor on the restoration of adrenal weight and cortical functions in hypophysectomized rats.
Hormones. 1970;1(5):257-72. doi: 10.1159/000178185.
3
4
[The state of the peripheral endocrine glands 14 months following hypophysectomy and their sensitivity to the tropic hormones of the hypophysis].[垂体切除术后14个月外周内分泌腺的状态及其对垂体促激素的敏感性]
Probl Endokrinol (Mosk). 1975 Jan-Feb;21(1):71-7.
5
Changes in the adrenal glands and other organs of intact and hypophysectomized rats following ACTH and adrenal steroids.促肾上腺皮质激素（ACTH）和肾上腺类固醇作用后，完整大鼠和垂体切除大鼠的肾上腺及其他器官的变化
Acta Endocrinol (Copenh). 1963;43:Suppl 82:1-28. doi: 10.1530/acta.0.043s003.
6
7
Effects of transplanted pituitary glands from non-arteriosclerotic virgin and arteriosclerotic breeder donors to hypophysectomized rats.将非动脉硬化的未交配供体和动脉硬化的繁殖期供体的垂体移植到垂体切除的大鼠体内的效果。
Acta Endocrinol (Copenh). 1968 Oct;59(2):249-60. doi: 10.1530/acta.0.0590249.
8
9
Endocrine interaction of the thymus with the hypohysis, adrenals and testes: effects of two thymic extracts.
Thymus. 1979 Sep;1(1-2):95-108.
10
Effect of imidazole on the adrenal response to ACTH and to stress.咪唑对肾上腺对促肾上腺皮质激素及应激反应的影响。
Acta Physiol Acad Sci Hung. 1972;42(3):225-30.
Zotero 插件