Marton J, Palfreyman J W, Schulster D
Mol Cell Endocrinol. 1976 Jun-Jul;5(1-2):147-9. doi: 10.1016/0303-7207(76)90077-0.
The effects of cholera on adrenal weight in hypophysectomized rats were investigated, in an attempt to demonstrate an ACTH-like, adrenal trophic effect of the toxin. The results suggested that the toxin probably exerts is ACTH-like action on the adrenal via adenylate cyclase. Cholera toxin was also shown to have a thermolytic action, similar to that of ACTH, probably due to stimulation of adrenal glucocorticoid secretion.
研究了霍乱对垂体切除大鼠肾上腺重量的影响，以试图证明该毒素具有促肾上腺皮质激素（ACTH）样的肾上腺营养作用。结果表明，该毒素可能通过腺苷酸环化酶对肾上腺发挥其ACTH样作用。霍乱毒素还显示出具有与ACTH类似的热分解作用，这可能是由于刺激了肾上腺糖皮质激素的分泌。
