Frerichs C C
Dev Biol Stand. 1976;33:321-7.
An H-120 strain of infectious bronchitis virus was prepared in a form suitable to serve as an international standard for Infectious Bronchitis Vaccine (live). Accelerated degradation studies carried out on this vaccine showed it to be of suitable stability to serve as a standard. Results from a collaborative assay involving ten laboratories demonstrated that the proposed standard reduced the variation in virus titrations both within and between laboratories. This assay also showed that firstly the proposed standard could be used as a reference vaccine for the different safety tests described by the collaborating laboratories, and secondly as a reference vaccine in the different potency tests.
制备了一种H - 120株传染性支气管炎病毒，其形式适合用作传染性支气管炎疫苗（活疫苗）的国际标准品。对该疫苗进行的加速降解研究表明，它具有适合作为标准品的稳定性。一项涉及十个实验室的协作试验结果表明，所提议的标准品减少了各实验室内部和实验室之间病毒滴定的差异。该试验还表明，首先，所提议的标准品可用作参与协作的各实验室所描述的不同安全性试验的参考疫苗，其次可用作不同效力试验中的参考疫苗。
