Saito Yuki, Toriumi Sayaka, Otake Rika, Suzuki Mitsuya
Department of Otolaryngology, Takeda General Hospital, Fukushima.
Nihon Jibiinkoka Gakkai Kaiho. 2008 Jan;111(1):21-4. doi: 10.3950/jibiinkoka.111.21.
Adult-onset Still's disease (AOSD) is characterized by fever, rash, and joint pain and may lead to chronic arthritis. The cause of AOSD is unknown, and it is rare. In children, Still's Disease is called systemic juvenile rheumatoid arthritis. We encountered a patient with adult-onset Still's disease following a severe sore throat and fever. The patient was a 17-year-old woman who consulted our hospital because of a sore throat and fever. She was admitted and treated with antibiotics, but the fever persisted. Laboratory parameters of inflammatory activity increased at an accelerated rate, and after ruling out sepsis, EBV-associated disease, and malignant lymphoma, a diagnosis of AOSD was made. Steroid therapy was very effective. When acute pharyngitis is observed in association with significant changes in laboratory parameters despite mild local symptoms, or when pharyngitis is observed in association with joint pain, continuous fever, and a rash, it is important to consider AOSI).
成人斯蒂尔病（AOSD）的特征为发热、皮疹和关节疼痛，可能会导致慢性关节炎。AOSD的病因不明，且较为罕见。在儿童中，斯蒂尔病被称为系统性幼年型类风湿关节炎。我们遇到了一名在严重咽痛和发热后患上成人斯蒂尔病的患者。该患者是一名17岁女性，因咽痛和发热前来我院就诊。她入院后接受了抗生素治疗，但发热持续不退。炎症活动的实验室指标加速上升，在排除败血症、EB病毒相关疾病和恶性淋巴瘤后，确诊为AOSD。类固醇治疗非常有效。当观察到急性咽炎伴有实验室指标的显著变化（尽管局部症状较轻），或者当咽炎伴有关节疼痛、持续发热和皮疹时，考虑成人斯蒂尔病很重要。
