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实施的价值与信息的价值:融合与不均衡发展

The value of implementation and the value of information: combined and uneven development.

作者信息

Fenwick Elisabeth, Claxton Karl, Sculpher Mark

机构信息

Public Health and Health Policy, University of Glasgow, Glasgow, UK.

出版信息

Med Decis Making. 2008 Jan-Feb;28(1):21-32. doi: 10.1177/0272989X07308751.

Abstract

AIM

In a budget-constrained health care system, the decision to invest in strategies to improve the implementation of cost-effective technologies must be made alongside decisions regarding investment in the technologies themselves and investment in further research. This article presents a single, unified framework that simultaneously addresses the problem of allocating funds between these separate but linked activities.

METHODS

The framework presents a simple 4-state world where both information and implementation can be either at the current level or "perfect.'' Through this framework, it is possible to determine the maximum return to further research and an upper bound on the value of adopting implementation strategies. The framework is illustrated through case studies of health care technologies selected from those previously considered by the UK National Institute for Health and Clinical Excellence (NICE).

RESULTS

Through the case studies, several key factors that influence the expected values of perfect information and perfect implementation are identified. These factors include the maximum acceptable cost-effectiveness ratio, the level of uncertainty surrounding the adoption decision, the expected net benefits associated with the technologies, the current level of implementation, and the size of the eligible population.

CONCLUSIONS

Previous methods for valuing implementation strategies have not distinguished the value of efficacy research and the value of strategies to change the level of implementation. This framework demonstrates that the value of information and the value of implementation can be examined separately but simultaneously in a single framework. This can usefully inform policy decisions about investment in health care services, further research, and adopting implementation strategies that are likely to differ between technologies.

摘要

目的

在预算有限的医疗保健系统中,决定投资于改善具有成本效益技术实施的策略时,必须同时做出关于技术本身投资和进一步研究投资的决策。本文提出了一个单一的统一框架,该框架同时解决了在这些相互独立但又相互关联的活动之间分配资金的问题。

方法

该框架呈现了一个简单的四状态世界,其中信息和实施都可以处于当前水平或“完美”状态。通过这个框架,可以确定进一步研究的最大回报以及采用实施策略的价值上限。通过从英国国家卫生与临床优化研究所(NICE)之前考虑过的医疗保健技术中选取的案例研究对该框架进行了说明。

结果

通过案例研究,确定了几个影响完美信息和完美实施预期值的关键因素。这些因素包括最大可接受成本效益比、采用决策周围的不确定性水平、与技术相关的预期净效益、当前实施水平以及符合条件的人群规模。

结论

以前评估实施策略的方法没有区分疗效研究的价值和改变实施水平策略的价值。这个框架表明,信息价值和实施价值可以在一个单一框架中分别但同时进行考察。这可以有效地为有关医疗保健服务投资、进一步研究以及采用可能因技术而异的实施策略的政策决策提供信息。

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