[将电休克疗法（ECT）与精神药物联合使用是否可取？]
[Is it advisable to combine electroconvulsive therapy (ECT) with psychotropics?].
作者信息
Kho K H
机构信息
Psychiater en vervangend A-opleider bij ggz Delfland te Delft.
出版信息
Tijdschr Psychiatr. 2008;50(2):99-104.
BACKGROUND
Psychotropic medication is sometimes tapered prior to electroconvulsive therapy (ECT) because of concern about interactions.
METHOD
The published literature is reviewed to find grounds for these concerns.
RESULTS
ECT can be combined safely with most psychotropics. Combination treatment with lithium can cause complications, but termination of lithium is not always necessary. Combination treatment with venlafaxin in doses higher than 300 mg daily can cause serious complications.
CONCLUSION
The recommendation in the Dutch guidelines not to combine ECT with psychotropics because of possible interactions needs to be reconsidered. A specific recommendation is needed for each psychotropic medication.
背景
由于担心相互作用，在进行电休克治疗（ECT）之前，有时会逐渐减少精神药物的使用。
方法
对已发表的文献进行综述，以寻找产生这些担忧的依据。
结果
ECT可以与大多数精神药物安全联合使用。与锂盐联合治疗可能会引起并发症，但并非总是需要停用锂盐。每日剂量高于300毫克的文拉法辛联合治疗可能会导致严重并发症。
结论
荷兰指南中因可能存在相互作用而不建议ECT与精神药物联合使用的建议需要重新考虑。每种精神药物都需要有具体的建议。
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