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Secreting tumor suppression.
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Oncogenic Braf induces melanocyte senescence and melanoma in mice.
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Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.
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Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer.
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The double-edged sword of autophagy modulation in cancer.
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Oncogene addiction: setting the stage for molecularly targeted cancer therapy.
Genes Dev. 2007 Dec 15;21(24):3214-31. doi: 10.1101/gad.1609907.
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Cellular senescence: when bad things happen to good cells.
Nat Rev Mol Cell Biol. 2007 Sep;8(9):729-40. doi: 10.1038/nrm2233.
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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
Nature. 2007 Feb 8;445(7128):656-60. doi: 10.1038/nature05529. Epub 2007 Jan 24.
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A negative feedback signaling network underlies oncogene-induced senescence.
Cancer Cell. 2006 Dec;10(6):459-72. doi: 10.1016/j.ccr.2006.10.003.
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Senescence comes of age.
Nat Med. 2005 Sep;11(9):920-2. doi: 10.1038/nm0905-920.
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Intrinsic tumour suppression.
Nature. 2004 Nov 18;432(7015):307-15. doi: 10.1038/nature03098.
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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS.
Exp Cell Res. 1965 Mar;37:614-36. doi: 10.1016/0014-4827(65)90211-9.
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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.
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