Whitwell Jennifer L, Josephs Keith A
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Parkinsonism Relat Disord. 2007;13 Suppl 3:S406-16. doi: 10.1016/S1353-8020(08)70039-7.
Voxel-based morphometry (VBM) is an automated technique that assesses patterns of regional grey and white matter atrophy on MRI between two groups of subjects. VBM has been used to assess patterns of regional atrophy in subjects with movement disorders. These studies have demonstrated specific patterns of regional loss in each disorder, compared different movement disorders to look for differences that could be diagnostically useful, and have correlated regions of loss to cognitive and motor deficits in these subjects. This article will review the findings of these studies and discuss the role of VBM in movement disorders.
基于体素的形态测量学（VBM）是一种自动化技术，用于评估两组受试者在MRI上区域灰质和白质萎缩的模式。VBM已被用于评估运动障碍患者的区域萎缩模式。这些研究已经证明了每种疾病中区域损失的特定模式，比较了不同的运动障碍以寻找可能具有诊断价值的差异，并将这些受试者的损失区域与认知和运动缺陷相关联。本文将综述这些研究的结果，并讨论VBM在运动障碍中的作用。
