Holm Søren
Cardiff Law School, Cardiff, UK.
Cells Tissues Organs. 2008;187(4):257-62. doi: 10.1159/000116763. Epub 2008 Feb 12.
Among the many ethical issues raised by human embryonic stem cell research (in the following all references to 'stem cells' should be read as references to human embryonic stem cells), two have gained specific prominence: (1) whether stem cell research is ethically problematic because it entails the destruction of human embryos and (2) what kind of control embryo donors should have over the stem cell lines derived from their embryos. In the present paper, I will analyse how these two issues are engaged by various attempts to derive stem cells from anomalous embryos (e.g. embryos in cleavage arrest, embryos not implanted following pre-implantation genetic diagnosis or embryos created by altered nuclear transfer) or in ways that are claimed to be non-destructive for the embryo (e.g. blastocyst or blastomere biopsy).
在人类胚胎干细胞研究引发的众多伦理问题中(以下所有提及的“干细胞”均应理解为人类胚胎干细胞),有两个问题尤为突出:(1)干细胞研究是否存在伦理问题,因为它涉及人类胚胎的破坏;(2)胚胎捐赠者对源自其胚胎的干细胞系应拥有何种控制权。在本文中,我将分析各种从异常胚胎(如卵裂阻滞的胚胎、植入前基因诊断后未植入的胚胎或通过改变核移植创建的胚胎)中获取干细胞的尝试,或者以声称对胚胎无损的方式(如囊胚或卵裂球活检)是如何处理这两个问题的。