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转化医学研究——一种新的生物伦理学方法的必要性。

Translational research-the need of a new bioethics approach.

作者信息

Hostiuc Sorin, Moldoveanu Alin, Dascălu Maria-Iuliana, Unnthorsson Runar, Jóhannesson Ómar I, Marcus Ioan

机构信息

Department of Legal Medicine and Bioethics, Carol Davila University, Bucharest, Romania.

National Institute of Legal Medicine, Bucharest, Romania.

出版信息

J Transl Med. 2016 Jan 15;14:16. doi: 10.1186/s12967-016-0773-4.

DOI:10.1186/s12967-016-0773-4
PMID:26767499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4714424/
Abstract

Translational research tries to apply findings from basic science to enhance human health and well-being. Many phases of the translational research may include non-medical tasks (information technology, engineering, nanotechnology, biochemistry, animal research, economy, sociology, psychology, politics, and so on). Using common bioethics principles to these areas might sometimes be not feasible, or even impossible. However, the whole process must respect some fundamental, moral principles. The purpose of this paper is to argument the need for a different approach to the morality in translational bioethics, and to suggest some directions that might be followed when constructing such a bioethics. We will show that a new approach is needed and present a few ethical issues that are specific to the translational research.

摘要

转化研究试图应用基础科学的研究成果来增进人类健康和福祉。转化研究的许多阶段可能包括非医学任务(信息技术、工程学、纳米技术、生物化学、动物研究、经济学、社会学、心理学、政治学等等)。将常见的生物伦理学原则应用于这些领域有时可能不可行,甚至是不可能的。然而,整个过程必须尊重一些基本的道德原则。本文的目的是论证在转化生物伦理学中需要一种不同的道德方法,并提出构建这种生物伦理学可能遵循的一些方向。我们将表明需要一种新方法,并提出一些转化研究特有的伦理问题。

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A discussion supporting presumed consent for posthumous sperm procurement and conception.关于支持死后精子采集与受孕的推定同意的讨论。
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Does Presumed Consent Save Lives? Evidence from Europe.推定同意能挽救生命吗?来自欧洲的证据。
通过行业支持的技术与教育支持模式推动医学技术创新与临床转化:印第安纳临床与转化科学研究所的医学技术推进项目
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The ethics of resource allocation in translational genomic medicine.转化基因组医学中的资源分配伦理
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