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退行性腰椎侧弯的短节段融合与长节段融合

Short fusion versus long fusion for degenerative lumbar scoliosis.

作者信息

Cho Kyu-Jung, Suk Se-Il, Park Seung-Rim, Kim Jin-Hyok, Kim Sung-Soo, Lee Tong-Joo, Lee Jeong-Joon, Lee Jong-Min

机构信息

Inha University Hospital, Incheon, Seoul, South Korea.

出版信息

Eur Spine J. 2008 May;17(5):650-6. doi: 10.1007/s00586-008-0615-z. Epub 2008 Feb 13.

Abstract

The extent of fusion for degenerative lumbar scoliosis has not yet been determined. The purpose of this study was to compare the results of short fusion versus long fusion for degenerative lumbar scoliosis. Fifty patients (mean age 65.5 +/- 5.1 years) undergoing decompression and fusion with pedicle screw instrumentation were evaluated. Short fusion was defined as fusion within the deformity, not exceeding the end vertebra. Long fusion was defined as fusion extended above the upper end vertebra. The lower end vertebra was included in the fusion in all the patients. The short fusion group included 28 patients and the long fusion group included 22 patients. Patients' age and number of medical co-morbidities were similar in both the groups. The number of levels fused was 3.1 +/- 0.9 segments in the short fusion group and 6.5 +/- 1.5 in the long fusion group. Before surgery, the average Cobb angle was 16.3 degrees (range 11-28 degrees ) in the short fusion group and 21.7 degrees (range 12-33 degrees ) in the long fusion group. The correction of the Cobb angle averaged 39% in the short fusion group and 72% in the long fusion group with a statistical difference (P = 0.001). Coronal imbalance improved significantly in the long fusion group more than in the short fusion group (P = 0.03). The correction of lateral listhesis was better in the long fusion group (P = 0.02). However, there was no difference in the correction of lumbar lordosis and sagittal imbalance between the two groups. Ten of the 50 patients had additional posterolateral lumbar interbody fusion at L4-5 or L5-S1. The interbody fusion had a positive influence in improving lumbar lordosis, but was ineffective at restoring sagittal imbalance. Early perioperative complications were likely to develop in the long fusion group. Late complications included adjacent segment disease, loosening of screws, and pseudarthrosis. Adjacent segment disease developed in ten patients in the short fusion group, and in five patients in the long fusion group. In the short fusion group, adjacent segment disease occurred proximally in all of the ten patients. Loosening of distal screws developed in three patients, and pseudarthrosis at L5-S1 in one patient in the long fusion group. Reoperation was performed in four patients in the long fusion group and three patients in the short fusion group. In conclusion, short fusion is sufficient for patients with small Cobb angle and good spinal balance. For patients with severe Cobb angle and rotatory subluxation, long fusion should be carried out to minimize adjacent segment disease. For patients who have severe sagittal imbalance, spinal osteotomy is an alternative technique to be considered. As long fusion is likely to increase early perioperative complications, great care should be taken for high-risk patients to avoid complications.

摘要

退行性腰椎侧凸的融合范围尚未确定。本研究的目的是比较退行性腰椎侧凸短节段融合与长节段融合的结果。对50例(平均年龄65.5±5.1岁)接受减压及椎弓根螺钉内固定融合术的患者进行了评估。短节段融合定义为在畸形范围内融合,不超过终椎。长节段融合定义为融合范围延伸至上端椎上方。所有患者的融合均包括下端椎。短节段融合组包括28例患者,长节段融合组包括22例患者。两组患者的年龄和合并症数量相似。短节段融合组融合节段数为3.1±0.9个,长节段融合组为6.5±1.5个。术前,短节段融合组平均Cobb角为16.3度(范围11 - 28度),长节段融合组为21.7度(范围12 - 33度)。短节段融合组Cobb角矫正平均为39%,长节段融合组为72%,差异有统计学意义(P = 0.001)。长节段融合组冠状面失衡改善明显大于短节段融合组(P = 0.03)。长节段融合组对侧方滑脱的矫正更好(P = 0.02)。然而,两组在腰椎前凸和矢状面失衡的矫正方面无差异。50例患者中有10例在L4 - 5或L5 - S1处进行了额外的腰椎后外侧椎间融合术。椎间融合术对改善腰椎前凸有积极影响,但对恢复矢状面失衡无效。长节段融合组早期围手术期并发症发生率较高。晚期并发症包括邻近节段疾病、螺钉松动和假关节形成。短节段融合组10例患者发生邻近节段疾病,长节段融合组5例。短节段融合组的10例患者中,邻近节段疾病均发生在近端。长节段融合组3例患者出现远端螺钉松动,1例患者在L5 - S1处发生假关节形成。长节段融合组4例患者和短节段融合组3例患者进行了再次手术。总之,对于Cobb角小且脊柱平衡良好的患者,短节段融合就足够了。对于Cobb角严重且伴有旋转半脱位的患者,应进行长节段融合以尽量减少邻近节段疾病。对于矢状面严重失衡的患者,脊柱截骨术是可考虑的替代技术。由于长节段融合可能增加早期围手术期并发症,对于高危患者应格外小心以避免并发症。

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